Results 101 to 110 of about 1,048,956 (299)

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

An untapped resource? Opportunities for faculty-librarian collaboration to enhance drug information resource utilization in pharmacy education. [PDF]

J Med Libr Assoc, 2022
Gill KD, Parker R.
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

BnPIR: Brassica napus pan-genome information resource for 1689 accessions. [PDF]

Plant Biotechnol J, 2021
Song JM, Liu DX, Xie WZ, Yang Z, Guo L, Liu K, Yang QY, Chen LL.   +7 more
europepmc   +1 more source

Enzymatic degradation of biopolymers in amorphous and molten states: mechanisms and applications

FEBS Open Bio, EarlyView.
This review explains how polymer morphology and thermal state shape enzymatic degradation pathways, comparing amorphous and molten biopolymer structures. By integrating structure–reactivity principles with insights from thermodynamics and enzyme engineering, it highlights mechanisms that enable efficient polymer breakdown.
Anđela Pustak, Aleksandra Maršavelski
wiley   +1 more source

Monitoring Dendrolimus punctatus Walker Infestations Using Sentinel-2: A Monthly Time-Series Approach

Remote Sensing
Infestations of Dendrolimus punctatus Walker (D. punctatus) pose significant threats to forest ecosystem health, necessitating accurate and efficient monitoring for sustainable forest management. A monthly monitoring framework integrating spectral bands,
Fangxin Meng, Xianlin Qin, Yakui Shao, Xinyu Hu, Feng Jiang, Shuisheng Huang, Linfeng Yu   +6 more
doaj   +1 more source

A Transgender Health Information Resource: Participatory Design Study.

JMIR Hum Factors, 2023
Morse B, Soares A, Kwan BM, Allen M, Lee RS, Desanto K, Holliman BD, Ytell K, Schilling LM.   +8 more
europepmc   +1 more source

PINIR: a comprehensive information resource for Pin-II type protease inhibitors. [PDF]

BMC Plant Biol, 2021
Yadav NK, Saikhedkar NS, Giri AP.
europepmc   +1 more source