Results 41 to 50 of about 7,826,212 (327)

DESIGNING OF SECONDARY SCHOOL INFORMATION ENVIRONMENT

open access: yesІнформаційні технології і засоби навчання, 2010
In the article the concept of «secondary school information environment» is considered, the problems concerning its creation are analyzed. There are determined purposes, problems and principles of information environment creation at school.
Oksana Ye. Kravchina
doaj  

The oldest medical library in Siberia (to the 70th anniversary of the Scientific-Medical Library of Siberian State Medical University)

open access: yesБюллетень сибирской медицины, 2005
The history of the oldest medical library in Siberia has been presented. There is data of the stock, information resources and the basic activity directions.
N. V. Molodtsova
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A Model for Evaluating Damage Inflicted Dye Destructive Events in the Computer Information System

open access: yesБезопасность информационных технологий, 2010
Here we present a model to evaluate the mean expectation of damage inflicted by destructive events in the computer information system. A condition of damage reduction is deduced. Some ways how to guarantee supply of this condition are presented.
S. V. Zapechnikov
doaj  

Collection Development of HIV/AIDS Information Resources in American Libraries [PDF]

open access: yes, 2011
HIV/AIDS remains an incurable epidemic in the United States that disproportionately affects men who have sex with men (MSM) and African Americans. Library and information science (LIS) professionals can play a vital role in keeping these higher risk ...
Andrews, Joseph G, Jr
core   +2 more sources

An intracellular transporter mitigates the CO2‐induced decline in iron content in Arabidopsis shoots

open access: yesFEBS Letters, EarlyView.
This study identifies a gene encoding a transmembrane protein, MIC, which contributes to the reduction of shoot Fe content observed in plants under elevated CO2. MIC is a putative Fe transporter localized to the Golgi and endosomal compartments. Its post‐translational regulation in roots may represent a potential target for improving plant nutrition ...
Timothy Mozzanino   +7 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Agricultural Information Needs and Resources of Smallholder Sugarcane Farmers in Swaziland

open access: yesLibri
The sugar industry is the dominant agricultural sector in Swaziland’s economy, contributing significantly to the gross domestic product. Provision of relevant and timely information to smallholder sugarcane farmers is crucial for them to have a ...
Dlamini Nkosinathi M., Ngulube Patrick
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

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