Results 71 to 80 of about 1,138,108 (315)
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
An evaluation resource for geographic information retrieval [PDF]
, 2008 In this paper we present an evaluation resource for geographic information retrieval developed within the Cross Language Evaluation Forum (CLEF). The GeoCLEF track is dedicated to the evaluation of geographic information retrieval systems. The resource
Di Nunzio, G. +6 more
core
Recommender Systems by means of Information Retrieval [PDF]
, 2010 In this paper we present a method for reformulating the Recommender Systems problem in an Information Retrieval one. In our tests we have a dataset of users who give ratings for some movies; we hide some values from the dataset, and we try to predict ...
Costa, Alberto, Roda, Fabio
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
, 2015 Retrieval and content management are assumed to be mutually exclusive. In this paper we suggest that they need not be so. In the usual information retrieval scenario, some information about queries leading to a website (due to `hits' or `visits') is ...
Chowdary, C Ravindranath +2 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
The Capacity of Private Information Retrieval
, 2017 In the private information retrieval (PIR) problem a user wishes to retrieve, as efficiently as possible, one out of $K$ messages from $N$ non-communicating databases (each holds all $K$ messages) while revealing nothing about the identity of the desired
Jafar, Syed A., Sun, Hua
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Optimizing poultry audio signal classification with deep learning and burn layer fusion
Journal of Big DataThis study introduces a novel deep learning-based approach for classifying poultry audio signals, incorporating a custom Burn Layer to enhance model robustness.
Esraa Hassan +4 more
doaj +1 more source