Results 71 to 80 of about 306,759 (292)

Bibliometric-Enhanced Information Retrieval [PDF]

open access: yes, 2014
6 pages, accepted workshop proposal for ECIR ...
Andrea Scharnhorst   +4 more
openaire   +4 more sources

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

A New Image Oversampling Method Based on Influence Functions and Weights

open access: yesApplied Sciences
Although imbalanced data have been studied for many years, the problem of data imbalance is still a major problem in the development of machine learning and artificial intelligence. The development of deep learning and artificial intelligence has further
Jun Ye, Shoulei Lu, Jiawei Chen
doaj   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Multimedia Information Retrieval Model

open access: yes, 2009
Given a collection of multimedia documents, the goal of multimedia information retrieval (MIR) is to find the documents that are relevant to a user information need. A multimedia document is a complex information object, with components of different kinds, such as text, images, video and sound, all in digital form.
Meghini C, Sebastiani F, Straccia U
openaire   +5 more sources

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

open access: yesFEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui   +15 more
wiley   +1 more source

Clinical entity-aware domain adaptation in low resource setting for inflammatory bowel disease

open access: yesFrontiers in Artificial Intelligence
The digitization of healthcare records has revolutionized medical research and patient care, with electronic health records (EHRs) containing a wealth of structured and unstructured data.
Sumam Francis   +5 more
doaj   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

A New Digital Signal Processing Based Model With Multi-Aspect Term Frequency for Information Retrieval

open access: yesIEEE Access, 2019
In recent decades, the vast majority of researchers in the field of information retrieval (IR) have been studying three main categories of IR models (i.e., vector space models, probabilistic models and statistical language models).
Zhiwei Ying   +2 more
doaj   +1 more source

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