Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Das liest die LIBREAS, Nummer #1 (Sommer / Herbst 2017)
Redaktion LIBREAS
doaj +1 more source
Quantum Models of Consciousness from a Quantum Information Science Perspective. [PDF]
Gassab L +3 more
europepmc +1 more source
Reimagining information science and technology beyond traditional boundaries in the global coronavirus pandemic situation. [PDF]
Rorissa A +4 more
europepmc +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
The role of information science within the clinical translational science ecosystem. [PDF]
Ragon B +22 more
europepmc +1 more source
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Was ist Informationswissenschaft und wenn ja, wie viele? Ein Veranstaltungsbericht
Carmen Krause
doaj +1 more source
Stable organic radical qubits and their applications in quantum information science. [PDF]
Zhou A, Sun Z, Sun L.
europepmc +1 more source
Applying interpretive phenomenological analysis to library and information science research on blended librarianship: A case study. [PDF]
Dabengwa IM, Raju J, Matingwina T.
europepmc +1 more source

