Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
La Documentación como ciencia integradora. Acercamiento sistemático a las unidades documentales
Anales de Documentación, 2006 Estructurado en dos partes: La Documentación como ciencia integradora y Acercamiento sistémico a las unidades documentales, este trabajo entiende la Documentación desde una perspectiva integradora traída del hermanamiento que supone el mismo modus ...
Rita Dolores Santaella Ruiz
doaj
Impacts of covid-19 pandemic in the Brazilian research scenario on misinformation: Analysis of publications from information science journals. [PDF]
J Librariansh Inf Sci, 2022 de Assis SSD, Gerlin MNM.
europepmc +1 more source
The Value of Information: A Background Paper on Measuring the Contribution of Space-Derived Earth Science Data to National Resource Management [PDF]
This study, prepared at the request of the Office of Earth Science at the U.S. National Aeronautics and Space Administration (NASA), describes a general framework for conceptualizing the value of information and illustrates how the framework might be ...
Macauley, Molly
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Ações de pesquisa e extensão no projeto laboratório de tecnologias intelectuais
TransinformaçãoEste trabalho apresenta os primeiros resultados do Projeto Laboratório de Tecnologias Intelectuais, em desenvolvimento mediante parceria entre o Departamento de Ciência da Informação e o Programa de Pós-Graduação em Ciência da Informação da Universidade ...
Isa Maria Freire +3 more
doaj
A scholarly network of AI research with an information science focus: Global North and Global South perspectives. [PDF]
PLoS One, 2022 Tang KY, Hsiao CH, Hwang GJ.
europepmc +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Knowledge Organization for Learning. Conjectures and Methods of Study
Ciência da Informação, 2015 This paper discusses and illustrates through examples how meaningful or deep learning can be supported through well-structured presentation of material, through giving learners schemas they can use to organize knowledge in their minds, and through ...
Dagobert Soergel
doaj
"OBE" Concept for New Training Mode of Electronic Information Science and Technology Professionals under Big Data Analysis. [PDF]
Comput Intell Neurosci, 2022 Liang J.
europepmc +1 more source