Results 81 to 90 of about 3,597,064 (317)

Targeting rapid TKI‐induced AXL upregulation overcomes adaptive ERK reactivation and exerts antileukemic effects in FLT3/ITD acute myeloid leukemia

Molecular Oncology, EarlyView.
Adaptive ERK reactivation hinders FLT3 tyrosine kinase inhibitor (TKI) treatment in FLT3/ITD acute myeloid leukemia. Here, we report that FLT3 TKI treatment rapidly induces AXL expression and upregulation that is temporally associated with the adaptive ERK reactivation.
Tessa S. Seale, Li Li, J. Kyle Bruner, Melody Chou, Bao Nguyen, Jaesung Seo, Ruiqi Zhu, Mark J. Levis, Christine A. Pratilas, Donald Small   +9 more
wiley   +1 more source

Ciência da informação: denominação de curso e diretrizes curriculares

Transinformação
Discussão das especificidade da Ciência da informação e da Arquivologia e de suas relações interdisciplinares.
Maria Odila Fonseca
doaj  

University Library Information Resources as a Basis for Enhancing Educational and Professional Programmes in Information, Library and Archival Studies

Acta Informatica Pragensia
The article aims to explore the role of information resources provided by university libraries in strengthening educational and professional programmes in the field of Information, Library and Archival Studies based on the Scientific Library of Kyiv ...
Nadiia Bachynska, Yurii Horban, Tetiana Novalska, Vladyslav Kasian, Nataliya Gaisynuik   +4 more
doaj   +1 more source

Combined spatially resolved metabolomics and spatial transcriptomics reveal the mechanism of RACK1‐mediated fatty acid synthesis

Molecular Oncology, EarlyView.
The authors analyzed the spatial distributions of gene and metabolite profiles in cervical cancer through spatial transcriptomic and spatially resolved metabolomic techniques. Pivotal genes and metabolites within these cases were then identified and validated.
Lixiu Xu, Jinqiu Li, Junqi Ma, Ayshamgul Hasim   +3 more
wiley   +1 more source

Web 2.1 : Toward a large and qualitative participation on the Web

Journal of Information and Organizational Sciences, 2009
This article presents the results of research done on Web 2.0 within the School of Information Sciences ESI. It aims to study the behavior of different academic actors who deal with information, among whom we cite teachers, students of masters and ...
Boubker Sbihi, Siham El jazouli, Kamal Eddine El kadiri   +2 more
doaj  

Reviews : Encyclopædia Britannica. A Dictionary of Arts, Sciences, Literature and General Information. Eleventh Edition. Twenty-nine vols. Price, $4.00 to $7.50 per volume. Cambridge, England, and New York: University Press, I9I0-I9II [PDF]

, 1911
Emory R. Johnson
openalex   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

Molecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld, Stefan Kühberger, Ricarda Graf, Christine Beichler, Markus Braun, Nadia Dandachi, Ellen Heitzer, Gerald W. Prager   +7 more
wiley   +1 more source

The silent barrier: exploring data availability in Small Island Developing States

Revista Panamericana de Salud Pública
Objective. To quantify three aspects of data-related developmental progress across 57 Small Island Developing States (SIDS) recognized by the United Nations: statistical capacity measured using the Statistical Performance Indicators (SPI), data ...
Ian Richard Hambleton, Selvi Jeyaseelan
doaj   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

You Can't Get There From Here: Redefining Information Science to address our sociotechnical futures [PDF]

arXiv
Current definitions of Information Science are inadequate to comprehensively describe the nature of its field of study and for addressing the problems that are arising from intelligent technologies. The ubiquitous rise of artificial intelligence applications and their impact on society demands the field of Information Science acknowledge the ...
arxiv