Results 21 to 30 of about 2,833,731 (301)

User Intent Prediction in Information-seeking Conversations

open access: yes, 2019
Conversational assistants are being progressively adopted by the general population. However, they are not capable of handling complicated information-seeking tasks that involve multiple turns of information exchange.
Bhatia S.   +15 more
core   +1 more source

Epistemic cooperation scripts in online learning environments [PDF]

open access: yes, 2005
Using online learning environments in higher education offers innovative possibilities to support collaborative learning. However, online learning creates new kinds of problems for participants who have not previously worked with each other. One of these
Fischer, Frank   +4 more
core   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Understanding Information Seeking Behavior of Indonesian Postgraduate Students in Malaysian Universities: an Empirical Study [PDF]

open access: yes, 2008
This study investigates Indonesian postgraduate student’s experience at the pre-sessional program of the process of seeking information and the strategies they used throughout the process.
Abdul Ghani, Ahmad Bashawir   +1 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Search procedures revisited [PDF]

open access: yes, 2010
Search Procedures reflects on a series of studies carried out over a four year period in the late 1970s. It was published at an interesting time for Information Retrieval.
Kelly, D., Ruthven, I.
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Information seeking in the Humanities: physicality and digitality [PDF]

open access: yes, 2008
This paper presents a brief overview of a research project that is examining the information seeking practices of humanities scholars. The results of this project are being used to develop digital resources to better support these work activities ...
Blandford, A.   +4 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Workshop on web information seeking and interaction [PDF]

open access: yes, 2007
The World Wide Web has provided access to a diverse range of information sources and systems. People engaging with this rich network of information may need to interact with different technologies, interfaces, and information providers in the course of a
Rodden, K., Ruthven, I., White, R. W.
core  

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