Results 41 to 50 of about 500,597 (217)

Students' Information Sources and Information-Seeking Challenges:

open access: yesInternational Journal of Librarianship
Academic libraries play a pivotal role in developing strategies to improve access to information, promote literacy, and offer support to students, particularly during unexpected events such as the pandemic.
Camia Lasig   +4 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Information Need and Information Seeking Behaviour

open access: yesTürk Kütüphaneciliği, 1997
Information need is one of the cognitive needs of humankind. Information need causes information seeking behaviour and these concepts complement each other. Information need and information seeking behaviour are effected by many factors.
Nazan Özenç Uçak
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Web information seeking by pages. World Wide Web, Information seeking, Personal development, Navigation

open access: yesInformation Research: An International Electronic Journal, 2004
The intention of this paper is to look at how the World Wide Web is used in looking for information in the domain of personal development. The theoretical aim of the paper is to elaborate conceptual tools for understanding better the content of Web pages,
Jarkko Kari
doaj  

Horse owners seeking online health information: a mixed-methods study

open access: yesFrontiers in Veterinary Science
BackgroundMany people seek health-related information online, not only for themselves but also on behalf of others who cannot articulate their symptoms.
Laura Haase   +5 more
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

A process Approach to Information Services: Information Search Process (ISP) Model

open access: yesIranian Journal of Information Processing & Management, 2010
Information seeking is a behavior emerging out of the interaction between information seeker and information system and should be regarded as an episodic process so as to meet information needs of users and to take different roles in different stages of ...
Hamid Keshavarz, Abaas Eslami
doaj  

A Meta-analysis of the factors affecting information seeking behavior in Iran and the world [PDF]

open access: yesتحقیقات اطلاع‌رسانی و کتابخانه‌های عمومی, 2020
Purpose: The aim of this study is to identify the components affecting information seeking behavior and to measure their impact from Persian and English articles in this field.
Elham Mirzaei   +2 more
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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