Results 41 to 50 of about 7,840,882 (325)

The Design of Information Technology as Design of the Information Society [PDF]

open access: yes, 2012
The design of technical product is often focused in the development of that particular artefact. However, when we introduce new technology we don’t simply replace old technology with new, but change many things in the whole context of use.
Maksimainen, Johanna   +2 more
core  

Identification of functional and diverse circulating cancer‐associated fibroblasts in metastatic castration‐naïve prostate cancer patients

open access: yesMolecular Oncology, Volume 19, Issue 7, Page 2074-2091, July 2025.
Cancer‐associated fibroblasts (CAFs) promote cancer growth, invasion (metastasis), and drug resistance. Here, we identified functional and diverse circulating CAFs (cCAFs) in patients with metastatic prostate cancer (mPCa). cCAFs were found in higher numbers and were functional and diverse in mPCa patients versus healthy individuals, suggesting their ...
Richell Booijink   +6 more
wiley   +1 more source

Bibliography and the information society

open access: yesBibliothecae.it, 2021
The paper offers reflection on the contribution that bibliography can offer to the information society. In recent decades, the role of information has become decisive not only as regards the cultural but also economic aspects of society.
Andrea Capaccioni
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, Volume 19, Issue 7, Page 1979-1997, July 2025.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Society as an information and communication technology [PDF]

open access: yes, 2002
“We explore the hypothesis that the social system (society) is not composed of human beings, but by their interactions and communications (Luhmann, 1984). Social order can then be considered as the complex dynamics of the expectations exchanges among us.”
Herron, Rebecca
core  

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

open access: yesMolecular Oncology, Volume 19, Issue 7, Page 1897-1917, July 2025.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker   +14 more
wiley   +1 more source

Examining database persistence of ISO/EN 13606 standardized electronic health record extracts: relational vs. NoSQL approaches

open access: yesBMC Medical Informatics and Decision Making, 2017
Background The objective of this research is to compare the relational and non-relational (NoSQL) database systems approaches in order to store, recover, query and persist standardized medical information in the form of ISO/EN 13606 normalized Electronic
Ricardo Sánchez-de-Madariaga   +6 more
doaj   +1 more source

Selection of indicators of information society development [PDF]

open access: yes, 2007
This paper examines problem of the evaluation of the information society development. The information society is a complex phenomenon and the evaluation of its development is highly complicated.
Pabedinskaite, Arnoldina
core  

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, Volume 19, Issue 7, Page 2092-2108, July 2025.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Information Society and Development

open access: yes, 1997
To harmonize the development process, it is important to provide guidelines for information exchange in developing countries. The national information system of the country should meet the informational and professional needs of researchers, planners, executives, consultants and educational groups.
openaire   +2 more sources

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