Results 51 to 60 of about 20,738,806 (379)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
An opinion as a structure element of the epistemic climate of knowledge society
Studia Humanitatis, 2018 The research offers to turn attention to the idea of the opinion society not as a systematic social-philosophical theory but as a concept to reveal the correlation of information and knowledge in the contemporary conditions; or to highlight the ...
Gоlubinskaya Anastasia Valerievna
doaj
FEBS Letters, EarlyView.Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
From Information Society to Knowledge Society: The Asian Perspective
Pakistan Journal of Information Management & Libraries, 2016 In an era, where ‘traditional society’ is replaced by a ‘knowledge society’, there is a global inclination towards creating knowledge and nurturing its affiliated factors.
Bilal Mehmood +2 more
doaj +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
What Can We Say about Information? Agreeing a Narrative [PDF]
, 2017 The nature of information remains contested. This paper proposes a set of principles for a narrative of information, and explores the consequences of taking these principles as normative in the present rhetoric of the information ...
Chapman, David
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
THE DECISION SUPPORT SYSTEMS FOR THE INFORMATION SOCIETY (i-Society) [PDF]
The globalization process needs exact information flows that should be collected in due time. The Information Society ensures the communication between people with different expertise from various geographical areas that have similar interests.
Virgil Chichernea
core
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
BMC Medical Informatics and Decision Making, 2017 Background The objective of this research is to compare the relational and non-relational (NoSQL) database systems approaches in order to store, recover, query and persist standardized medical information in the form of ISO/EN 13606 normalized Electronic
Ricardo Sánchez-de-Madariaga +6 more
doaj +1 more source