Results 91 to 100 of about 15,515,363 (286)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Identity Authentication Using Portable Electroencephalography Signals in Resting States

open access: yesIEEE Access, 2019
Biometric identity authentication technology is widely used in the field of information security. As a new biological method, electroencephalography (EEG) is gradually applied in biometric recognition, because scientists believe that practicability and ...
Rongkai Zhang   +5 more
doaj   +1 more source

Immunization Information Systems [PDF]

open access: yesPediatrics, 2006
The American Academy of Pediatrics continues to support the development and implementation of immunization information systems, previously referred to as immunization registries, and other systems for the benefit of children, pediatricians, and their communities.
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Information System Design for Micro Credit Banks [PDF]

open access: yes, 2003
Developments in the banking system under its wings for small entrepreneurs (market traders)who very much and is the economic backbone of the people in Indonesia. To assist the smallentrepreneurs who are usually very shy in touch with the bank. This micro-
Widianti, L. W. (Linda)
core  

Developing a Reference for Smart Rural Communities: An Enterprise Architecture Perspective for Smart Governance

open access: yesJurnal Sistem Informasi
The digital transformation of rural governance is critical to achieving Sustainable Development Goals (SDGs) and fostering community self-reliance.
Intania Fadya Safitri   +2 more
doaj   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Employee Salary Information System Off Labor Department Data Management in PT Infomedia Nusantara Using Microsoft Access 2000 [PDF]

open access: yes, 2005
With this system freelance payroll was on time. The calculation of overtime pay and freelance employees are in accordance with the realization that exist. Similarly, in terms of salaries of employees reporting to the CEO was on time.
Damiyati, H. (Heny)   +1 more
core  

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Pengaruh Information Quality, System Quality, dan Service Quality terhadap Perceived Flow (Studi Kasus pada Pengguna Aplikasi Traveloka) [PDF]

open access: yes, 2018
Penelitian ini bertujuan untuk menguji Pengaruh Information Quality, System Quality, dan Service Quality terhadap Perceived Flow. Penelitian ini dilakukan pada 195 responden di Yogyakarta dengan responden para pengguna Aplikasi Traveloka yang melakukan ...
Saputra, H. O. (Henry)
core  

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