Results 111 to 120 of about 15,663,128 (307)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Recording Information System for Goods Owned Inventory/ Asset State Environment Water Resources Directorate of the Central Region Using Unified Modeling Language (Uml) and Visual Basic. Net [PDF]

, 2006
The increasing activities of environmental goods inventory records of Water Resources Directorate of the Central Region and the growing need for a wide range of information the writer trying to help create a system of recording information goods.
Melani Dewi Lusita, SKom, MMSI, YUSUF, M. (MUHAMMAD)   +1 more
core  

Information Loss in the Human Auditory System

, 2018
From the eardrum to the auditory cortex, where acoustic stimuli are decoded, there are several stages of auditory processing and transmission where information may potentially get lost.
Jahromi, Mohsen Zareian, Jensen, Jesper, Zahedi, Adel, Østergaard, Jan   +3 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

House Sales Information System in Branch III Unit Perumnas Karawaci [PDF]

, 1998
In order to improve utilization of system processing sales information at branch III PERUMNAS Karawaci unit, then a system needs a good data handling and can provide information quickly. Efforts to address these needs with speed and accuracy is high. The
Aqwam Rosadi Kardian,S.kom.,MMSI, Priyono, P. (Priyono)   +1 more
core  

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Study Information System Scheduling Based on Procurement of Goods in Connection with the Goods in Inventory Control PT. Usi-jaya [PDF]

, 1990
One of the major factors that support the production is the supply of goods, inaddition to the human / labor, machinery, and capital. Duty management arranged forthe above factors can work together to produce maximum output with minimuminput. Inventories
Sadikin, M. A. (M), Wahab, S. (Sulwan)
core  

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Geoid Undulation Model as Vertical Reference in Indonesia

Scientific Data
Indonesia released a new regional geoid model in 2020—the Indonesian Geoid 2020 (INAGEOID2020). It covers the Indonesian region with a spatial resolution of 0.01 × 0.01 degree with the unit in meters.
Arisauna Pahlevi, Agustina Syafarianty, Susilo Susilo, Yustisi Lumban-Gaol, Widy Putra, Bagas Triarahmadhana, Brian Bramanto, Raa Muntaha, King El Fadhila, Febriananda Ladivanov, Harka Amrossalma, Lukman Islam, Dwi Novianto, Safirotul Huda, Tunjung Wismadi, Joni Efendi, Alkindi Ramadhan, Dudy Wijaya, Kosasih Prijatna, Gatot Pramono   +19 more
doaj   +1 more source