Results 121 to 130 of about 36,992,088 (301)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Geoid Undulation Model as Vertical Reference in Indonesia
Scientific DataIndonesia released a new regional geoid model in 2020—the Indonesian Geoid 2020 (INAGEOID2020). It covers the Indonesian region with a spatial resolution of 0.01 × 0.01 degree with the unit in meters.
Arisauna Pahlevi +19 more
doaj +1 more source
Information system upon information systems : a conceptual framework
, 2004 Our research addresses the problem of managing and coordinating information resources used in information system (IS) development. In our approach, we argue that conceptual specifications of information systems are the fundamental constituents of information resources.
openaire +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Information strategies for Geographical Information Systems
International Journal of Geographical Information Science, 1998 Recently, several publications have appeared that relate to the strategic dimension of GIS: how can GIS be aligned with business strategies, what strategic opportunities does GIS offer? In the broad range of elements identified in these discussions the critical observer will find quite different connotations of the concept of 'information strategy ...
openaire +2 more sources
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Other title: Retirement Planning and the Regulations Affecting Benefits
, 2009 application/pdfA set of 12 documents provided by the Kansas Public Employees Retirement System with resources and information on Retirement Planning and the Regulations Affecting Benefits.Investment Expertise: Keenly Dedicated to Growing Assets for ...
Kansas Public Employees Retirement System.
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source