Results 71 to 80 of about 2,120,304 (301)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Resource Management Based on Security Satisfaction Ratio with Fairness-Aware in Two-Way Relay Networks

International Journal of Distributed Sensor Networks, 2015
Information security has been received more and more attention for next-generation wireless sensor networks. In this paper, we consider the problem of resource management based on security satisfaction ratio with fairness-aware in two-way relay networks.
Jun Zhao, Zhaoming Lu, Xiangming Wen, Haijun Zhang, Shenghua He, Wenpeng Jing   +5 more
doaj   +1 more source

Artequakt: Generating tailored biographies from automatically annotated fragments from the web [PDF]

, 2002
The Artequakt project seeks to automatically generate narrativebiographies of artists from knowledge that has been extracted from the Web and maintained in a knowledge base.
Alani, Harith, Hall, Wendy, Kim, Sanghee, Lewis, Paul, Millard, David, Shadbolt, Nigel, Weal, Mark   +6 more
core  

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Information System Architectures: Representation, Planning and Evaluation [PDF]

Journal of Systemics, Cybernetics and Informatics, 2003
In recent years organizations have been faced with increasingly demanding business environments - pushed by factors like market globalization, need for product and service innovation and product life cycle reduction - and with new information ...
André Vasconcelos, Pedro Sousa, José Tribolet   +2 more
doaj  

Multilevel Continuous Polarization Modulation With High Spectral Efficiency in the Depolarization Channels

IEEE Access, 2018
Facing the challenges of spectrum shortage and complex depolarization effects in wireless communication, a multilevel continuous polarization modulation (MCPoM) scheme is investigated to achieve high spectral efficiency and improve the symbol error rate ...
Fangfang Liu, Xinyi Wang, Ruomeng Li, Bingcheng Wang   +3 more
doaj   +1 more source

A Dimmable OFDM Scheme With Dynamic Subcarrier Activation for VLC

IEEE Photonics Journal, 2020
Dimmable optical orthogonal frequency division multiplexing (D-OFDM) is challenging to design for visible light communications, due to the high peak-to-average power ratio (PAPR) of OFDM signals and limited dynamic range of LEDs.
Congcong Wang, Yang Yang, Julian Cheng, Caili Guo, Chunyan Feng   +4 more
doaj   +1 more source

Advanced information processing system for advanced launch system: Avionics architecture synthesis [PDF]

The Advanced Information Processing System (AIPS) is a fault-tolerant distributed computer system architecture that was developed to meet the real time computational needs of advanced aerospace vehicles.
Alger, Linda S., Harper, Richard E., Jaskowiak, Kenneth R., Lala, Jaynarayan H., Rosch, Gene, Schor, Andrei L.   +5 more
core   +1 more source