Results 81 to 90 of about 2,120,304 (301)
FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
An Architecture for Information Commerce Systems [PDF]
, 2001 The increasing use of the Internet in business and commerce has created a number of new business opportunities and the need for supporting models and platforms.
Di Nitto, Elisabetta +5 more
core +3 more sources
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
COVID-19, Data architecture, Information system, Reportable diseases, Surveillance system
Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2021 Introduction: Management and control of reportable diseases are challenging because these diseases include a large spectrum of infectious conditions that need accurate, precise, and timely reporting.
Mostafa Shanbehzadeh +5 more
doaj
A generic architecture and dialogue model for multimodal interaction [PDF]
, 2003 This paper presents a generic architecture and a dialogue model for multimodal interaction. Architecture and model are transparent and have been used for different task domains.
Akker, H.J.A. op den +2 more
core +2 more sources
Building a Generation Knowledge Source using Internet-Accessible Newswire
, 1997 In this paper, we describe a method for automatic creation of a knowledge source for text generation using information extraction over the Internet. We present a prototype system called PROFILE which uses a client-server architecture to extract noun ...
McKeown, Kathleen R., Radev, Dragomir R.
core +2 more sources
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
An Architectural Approach to Cognitive Information Systems
Acta Polytechnica Hungarica, 2019 The fast changes in information technology and business needs led to the evolution and development of Cognitive Information Systems (CIS). There have been few researches on the general model for analysis and design of CIS. This paper attempts to create a design scheme for incorporating the various model for CISs and Understanding-based management ...
Balint Molnar +1 more
openaire +1 more source
Large-Scale User Behavior Characterization of Online Video Service in Cellular Network
IEEE Access, 2016 Online video service has become prevalent in recent years. A better understanding of the user behavior of such service is crucial for allocating the network resources and adjusting the service design.
Chenyu Li, Jun Liu, Shuxin Ouyang
doaj +1 more source
A fault-tolerant multiprocessor architecture for aircraft, volume 1 [PDF]
A fault-tolerant multiprocessor architecture is reported. This architecture, together with a comprehensive information system architecture, has important potential for future aircraft applications.
Ausrotas, R. A. +6 more
core +1 more source