Results 191 to 200 of about 1,715,165 (266)

Efficient EEG channel-and-frequency-band selection for epileptic seizure classification using multi-objective optimization. [PDF]

Front Neurol
Chen W, Lei X, Guo H, Zhuang L.
europepmc   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

An optimization method for railway alignment schemes based on game-theoretic combination weighting and an interval number model. [PDF]

Sci Rep
Yang D, Han F, Gao Y, Li Z.
europepmc   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Metabolomics for plant breeding: knowledge without adoption. [PDF]

Front Plant Sci
Pacheco-Ruiz P, Postacchini S, Mazzoni L, Vallarino JG.   +3 more
europepmc   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Privacy-Preserving Hybrid GA-LSTM Ensemble for Typhoid Detection Using Optimised Clinical Feature Selection. [PDF]

Biomedicines
Gasmi K, Alanazi A, Almenwer S, Almaghrabi S, Alshammari H, Khaldi K, Chouaib H.   +6 more
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Number-action coupling across the lifespan: Sensorimotor foundations of numerical cognition. [PDF]

iScience
Prabhu S, Giraud M, Noacco S, Brigadoi S, Mioni G, Cutini S, Saccani MS, Ranzini M, Nava E.   +8 more
europepmc   +1 more source

Learning to dispatch volunteers to out-of-hospital cardiac arrests. [PDF]

Health Care Manag Sci
van den Berg PL, Fourmentraux O, Henderson SG, Jagtenberg CJ, Li H.   +4 more
europepmc   +1 more source