Results 61 to 70 of about 1,715,165 (266)

INITIATION AND PLANNING OF AN INFORMATION SYSTEM. A CASE STUDY. [PDF]

Annals of the University of Craiova: Economic Sciences Series, 2021
Starting from the premise of the importance of the information system in the good development of the contemporary economic life, this paper proposes a presentation of the steps necessary to initiate and plan the process of creating an information system,
Cristian Dragos Turcan, Viorel - Costin Banta, Sabin – Alexandru Babeanu   +2 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Matrix Method for the Optimal Scale Selection of Multi-Scale Information Decision Systems

Mathematics, 2019
In multi-scale information systems, the information is often characterized at multi scales and multi levels. To facilitate the computational process of multi-scale information systems, we employ the matrix method to represent the multi-scale information ...
Ying Sheng Chen, Jin Jin Li, Jian Xin Huang   +2 more
doaj   +1 more source

Outage Analysis and Learning-Based Relay Selection for Opportunistic Lossy Forwarding Relaying Systems

IEEE Access, 2020
In this paper, we study an opportunistic decode-and-forward (DF) system allowing intra-link errors, referred as opportunistic lossy-forwarding (OLF) system.
Haiyang Zhang, Zhiwei Zhang
doaj   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

GIS-based Locating of Suitable Orchards for Organic Apple Production in Urmia [PDF]

Journal of Agricultural Science and Sustainable Production, 2016
suitable location for organic apple production is the important factors involved in site selection including elevation, slope of land, access to water, land units, the average annual temperature and average rain fall and access to markets, each with more
Reza Rezaee, Behzad Hesari
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source