Results 131 to 140 of about 4,020,268 (318)
Protecting information in systems of systems
, 2011 Systems of Systems (SoS) are dynamic, distributed coalitions of autonomous and heterogeneous systems that collaborate to achieve a common goal. While o¿ering several advantages in terms of scalability and ¿exibility, the SoS paradigm has a strong impact on system interoperability and on the security requirements of collaborating parties.
Trivellato, Daniel +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Impact of Mobility on Information Systems and Information System Design
, 2004 The subject of this thesis is to analyse the impact of mobile hardware and software on information systems, to survey existing approaches for specifying mobile systems of computer science in general, and to provide suitable means for the formal design of information systems comprising such mobile units in particular. We consider a mobile unit to denote
openaire +3 more sources
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The deterrent and displacement effects of information security enforcement: International evidence
, 2008 10.2753/MIS0742-1222250206Journal of Management Information Systems252125 ...
Wang, C.-Y. +9 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The Information Systems Academic Discipline in Singapore 2006
, 2007 The global downturn in demand for IT skills has not left Singapore unscathed. While the demand for information systems graduates has not been as adversely affected as that for traditional computer science ones, there appears to be a drop in the entry ...
Tan, Bernard C.Y., Chan, Taizan
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Information strategies for Geographical Information Systems
International Journal of Geographical Information Science, 1998 Recently, several publications have appeared that relate to the strategic dimension of GIS: how can GIS be aligned with business strategies, what strategic opportunities does GIS offer? In the broad range of elements identified in these discussions the critical observer will find quite different connotations of the concept of 'information strategy ...
openaire +2 more sources