Results 111 to 120 of about 4,020,268 (318)
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
An alternative theory of legacy information systems
, 2003 Organisational dependence upon IT continues to grow yet experiences of satisfaction vary widely. Problematic, aged IT is often cited as being a fundamental problem in this respect and this is commonly termed legacy information systems.
Light, Ben
core
, 2019 This paper investigates the concept of data collection in information systems qualitative research. In this text, I replace the term “data collection” with “data generation” to emphasize that the researcher arranges situations that produce rich and ...
Goldkuhl, Göran, Goldkuhl, Göran,
core +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
, 2005 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Our work will be mainly concerned with improving the crucial first stage (the requirements stage) of any system development methodology in order to improve ...
Al-Karaghouli, Wafi Yousif Ramadaan
core
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Changes in Customer Behavior Towards Video Advertising Post-Pandemic
Journal of Information Systems Engineering and Business IntelligenceBackground: Video Advertising (VI) is a powerful media tool used by several companies as a marketing strategy. During COVID-19 pandemic, there was a wide adoption of digital media, particularly VI, to promote company products.
Surjandy Surjandy, Cadelina Cassandra
doaj +1 more source
Information system upon information systems : a conceptual framework
, 2004 Our research addresses the problem of managing and coordinating information resources used in information system (IS) development. In our approach, we argue that conceptual specifications of information systems are the fundamental constituents of information resources.
openaire +2 more sources
The Work System Method for Understanding Information Systems and Information Systems Research
Communications of the Association for Information Systems, 2002 The work system method is a broadly applicable set of ideas that use the concept of “work system” as the focal point for understanding, analyzing, and improving systems in organizations, whether or not IT is involved. The premises underlying this method may be controversial in the IS community because they imply that the traditional jargon and concerns
openaire +3 more sources
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source