Results 121 to 130 of about 26,803,103 (290)

Impact of Mobility on Information Systems and Information System Design

open access: yes, 2004
The subject of this thesis is to analyse the impact of mobile hardware and software on information systems, to survey existing approaches for specifying mobile systems of computer science in general, and to provide suitable means for the formal design of information systems comprising such mobile units in particular. We consider a mobile unit to denote
openaire   +3 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Scaling up repowering decisions: a farm-level financial decision support system for onshore wind energy assets

open access: yesEnergy Informatics
The aging of wind energy assets and the expiration of government subsidies make decisions on continued operation, repowering, and decommissioning increasingly critical for wind farm operators.
Yifan Wang   +3 more
doaj   +1 more source

Assessing the Maturity Level of Open Ticket Services Using ITIL V4 Framework

open access: yesJournal of Applied Informatics and Computing
Information technology services are fundamental in facilitating academic operations within higher education institutions. One essential component of IT service delivery is a ticket-based system designed to manage user-reported incidents and service ...
Arvhi Randita Setia   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Information system upon information systems : a conceptual framework

open access: yes, 2004
Our research addresses the problem of managing and coordinating information resources used in information system (IS) development. In our approach, we argue that conceptual specifications of information systems are the fundamental constituents of information resources.
openaire   +2 more sources

The Work System Method for Understanding Information Systems and Information Systems Research

open access: yesCommunications of the Association for Information Systems, 2002
The work system method is a broadly applicable set of ideas that use the concept of “work system” as the focal point for understanding, analyzing, and improving systems in organizations, whether or not IT is involved. The premises underlying this method may be controversial in the IS community because they imply that the traditional jargon and concerns
openaire   +3 more sources

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A systematic review of machine learning algorithms for mortality risk, readmission and phenotype prediction in patients with heart failure: exploring key data sources, input variables and outcomes

open access: yesBMC Medical Informatics and Decision Making
Background Heart failure is not only a prevalent disease with a high mortality rate, but also generates high costs for healthcare systems. By training artificial intelligence (AI) models on medical data, it is possible to predict changes in health status
Aleksandra Flok   +3 more
doaj   +1 more source

Information Systems [PDF]

open access: yesYearbook of Medical Informatics, 1994
openaire   +2 more sources

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