Results 131 to 140 of about 22,452,588 (375)

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Smart Summary: A Distributed Medical Recommender System for Patients in the ICU Using Neural Networks

IEEE Access
In the medical domain, particularly in intensive care units (ICUs), the immense volume of patient data presents a significant challenge for clinicians, often resulting in the oversight of critical information or excessive time consumption in accessing it.
Ahmad Ayad, Yu-Hsuan Tai, Guido Dartmann, Anke Schmeink   +3 more
doaj   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Estimating ecoacoustic activity in the Amazon rainforest through Information Theory quantifiers

, 2020
Juan G. Colonna, José Reginaldo H. Carvalho, Osvaldo A. Rosso   +2 more
openalex   +1 more source

Theory of solid state quantum information processing

, 2004
Recent theoretical work on solid-state proposals for the implementation of quantum computation and quantum information processing is reviewed. The differences and similarities between microscopic and macroscopic qubits are highlighted and exemplified by ...
Burkard, Guido
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

IEEE Transactions on Information Theory Publication Information [PDF]

, 2022
Christina Fragouli, Parastoo Sadeghi, Edmund Yeh, Muriel dard, P Kumar, Matthieu Bloch, Junior Past, Senior Past, Mario Berta Quantum, Matthieu Security, Marco Dalai, Varun Jog, Thomas Johansson, Oliver Johnson, Shannon Theory, Information Measures, Daniel Katz, Mari Kobayashi Communications, Tobias Communications, Stefano Mancini, David Mitchell, Pradeep Kiran, Sarvepalli Quantum, Vincent Tan, Machine Learning, Statistics Ravi, Tandon Security, Tchamkerten Shannon, Antonia Wachter, Yang Sheng, Xinbing Communications, Wang, K Liu, Saifur Rahman, John Walz, Ellen Randall, Kathy Land, Stephen Phillips, Sergio Benedetto, David Koehler, James Matthews, Standards Association, Bruno Meyer, Deborah Cooper, Ali Sayed, Sophia Muirhead, Cherif Amirat, Chris Brantley, Karen Hawkins, Steven Heffner, Donna Hourican, Cecelia Jankowski, Geographic Activities, Konstantinos Karachalios, Ieee-Standards Association, Jamie Moesch, Thomas Siegert, Mary Ward-Callan   +57 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

Fog Computing Meets URLLC: Energy Minimization of Task Partial Offloading for URLLC Services

IEEE Access
Ultra-high reliability and ultra-low latency communication (URLLC) are critical challenges for upcoming 6G applications. Cloud computing and mobile edge computing (MEC) offer potential solutions but incur high deployment and maintenance costs due to ...
Chenhao Shi, Jingrui Wei, Yao Zhu, Anke Schmeink   +3 more
doaj   +1 more source

Fusion of Identification Information from ESM Sensors and Radars Using Dezert-Smarandache Theory Rules

, 2023
Tadeusz Pietkiewicz
openalex   +2 more sources