Results 131 to 140 of about 16,404,119 (364)

Informed Grounded Theory

open access: yesScandinavian Journal of Educational Research, 2012
There is a widespread idea that in grounded theory (GT) research, the researcher has to delay the literature review until the end of the analysis to avoid contamination – a dictum that might turn educational researchers away from GT. Nevertheless, in this article the author (a) problematizes the dictum of delaying a literature review in classic ...
openaire   +4 more sources

KMT2A degradation is observed in decitabine‐responsive acute lymphoblastic leukemia cells

open access: yesMolecular Oncology, EarlyView.
We demonstrate that decitabine (DEC) not only degrades the DNA methyltransferase DNMT1 but also the leukemic driver lysine methyltransferase KMT2A likely due to structural similarity of the DNA‐binding CXXC domains. DEC influences KMT2A downstream processes and synergizes with menin inhibitor revumenib (REV) to decrease leukemic cell proliferation, and
Luisa Brock   +10 more
wiley   +1 more source

A Completion Time-Based Flow Scheduling for Inter-Data Center Traffic Optimization

open access: yesIEEE Access, 2018
With the rise of cloud computing service, traffic in inter-data center wide area networks (inter-DC WANs) has been growing rapidly. Inter-data center traffic contains multitudinous data transfers that require to be accomplished within certain time ...
Wenbo Hu   +3 more
doaj   +1 more source

A Synergetic Theory of Information [PDF]

open access: yesInformation, 2019
A new approach is presented to defining the amount of information, in which information is understood as the data about a finite set as a whole, whereas the average length of an integrative code of elements serves as a measure of information. In the framework of this approach, the formula for the syntropy of a reflection was obtained for the first time,
openaire   +3 more sources

Polyfunctional CD8+CD226+RUNX2hi effector T cells are diminished in advanced stages of chronic lymphocytic leukemia

open access: yesMolecular Oncology, EarlyView.
CD226+CD8+ T cells express elevated levels of RUNX2, exhibit higher proliferation capacity, cytokines and cytolytic molecules expression, and migratory capacity. In contrast, CD226−CD8+ T cells display an exhausted phenotype associated with the increased expression of co‐inhibitory receptors and impaired effector functions.
Maryam Rezaeifar   +4 more
wiley   +1 more source

Algorithmic Information Theory: a brief non-technical guide to the field [PDF]

open access: yesScholarpedia, 2:3 (2007) page 2519, 2007
This article is a brief guide to the field of algorithmic information theory (AIT), its underlying philosophy, and the most important concepts. AIT arises by mixing information theory and computation theory to obtain an objective and absolute notion of information in an individual object, and in so doing gives rise to an objective and robust notion of ...
arxiv  

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

open access: yesMolecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy   +12 more
wiley   +1 more source

Cystatin A promotes the antitumor activity of T helper type 1 cells and dendritic cells in murine models of pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti   +8 more
wiley   +1 more source

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