Results 151 to 160 of about 21,680,450 (363)

Beyond cytotoxic T cells: reprogrammed regulatory T cells help facilitate response to dual checkpoint blockade

open access: yesMolecular Oncology, EarlyView.
Rolig, Peng, and colleagues have shed new light on how dual blockade of PD1 and LAG3 enhances antitumor immunity. They found that response to immunotherapy with anti‐PD1 + anti‐LAG3 was associated with reprogramming of canonically suppressive CD4+ regulatory T cells to an inflammatory state.
Tullia C. Bruno, Anthony R. Cillo
wiley   +1 more source

Fog Computing Meets URLLC: Energy Minimization of Task Partial Offloading for URLLC Services

open access: yesIEEE Access
Ultra-high reliability and ultra-low latency communication (URLLC) are critical challenges for upcoming 6G applications. Cloud computing and mobile edge computing (MEC) offer potential solutions but incur high deployment and maintenance costs due to ...
Chenhao Shi   +3 more
doaj   +1 more source

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Modeling Information Propagation with Survival Theory

open access: yes, 2013
Networks provide a skeleton for the spread of contagions, like, information, ideas, behaviors and diseases. Many times networks over which contagions diffuse are unobserved and need to be inferred.
Leskovec, Jure   +2 more
core  

Information structure and information theory

open access: yes
Synopsis: This volume results from the workshop "Discourse obligates – How and why discourse limits the way we express what we express" at the 44th Annual Meeting of the German Linguistic Society in Tübingen, Germany. The workshop brought - and this book brings - together information-structural and information-theoretic perspectives on optional ...
Lemke, Robin   +2 more
openaire   +2 more sources

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

What is Integrated Information Theory a Theory Of? [PDF]

open access: yes
In the first instance, IIT is formulated as a theory of the physical basis of the 'degree' or ‘level’ or ‘amount’ of consciousness in a system. I raise a series of questions about the central explanatory target, the 'degree' or ‘level’ or ‘amount’ of ...
Pautz, Adam
core  

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