Results 81 to 90 of about 1,024,528 (268)
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Low-Complexity Gaussian Detection for MIMO Systems
For single-carrier transmission over delay-spread multi-input multi-output (MIMO) channels, the computational complexity of the receiver is often considered as a bottleneck with respect to (w.r.t.) practical implementations.
Tianbin Wo, Peter Adam Hoeher
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Disjoint Pilot Power and Data Power Allocation in Multi-Cell Multi-User Massive MIMO Systems
In this paper, we consider pilot and data power allocation in multi-cell multi-user massive multiple-input multiple-output (MIMO) systems to maximize the summation of spectral efficiency (sum SE).
Hieu Trong Dao, Sunghwan Kim
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Texture recognition under scale and illumination variations
Visual scene recognition is predominantly based on visual textures representing an object's material properties. However, the single material texture varies in scale and illumination angles due to mapping an object's shape. We present a comparative study
Pavel Vácha, Michal Haindl
doaj +1 more source
A Completion Time-Based Flow Scheduling for Inter-Data Center Traffic Optimization
With the rise of cloud computing service, traffic in inter-data center wide area networks (inter-DC WANs) has been growing rapidly. Inter-data center traffic contains multitudinous data transfers that require to be accomplished within certain time ...
Wenbo Hu +3 more
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source

