Results 71 to 80 of about 2,285,691 (245)

Real‐World Investigation of Satralizumab in Patients With Neuromyelitis Optica Spectrum Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Satralizumab, a monoclonal antibody targeting the interleukin‐6 receptor, has demonstrated efficacy in clinical trials for neuromyelitis optica spectrum disorder (NMOSD). However, its real‐world effectiveness and safety compared to conventional immunosuppressive therapies remain uncertain.
Li‐Tsung Lin   +2 more
wiley   +1 more source

Facing a future water resources management crisis in sub-Saharan Africa

open access: yesJournal of Hydrology: Regional Studies, 2019
Study region: Sub-Saharan Africa. Study focus: Water resources availability assessments are highly uncertain due to inadequate observation networks, and this is expected to get worse into the future. This uncertainty is expected to increase in the future
D.A. Hughes
doaj   +1 more source

From Sensor to Observation Web with Environmental Enablers in the Future Internet [PDF]

open access: yes, 2011
This paper outlines the grand challenges in global sustainability research and the objectives of the FP7 Future Internet PPP program within the Digital Agenda for Europe. Large user communities are generating significant amounts of valuable environmental
Berre, Arene J.   +6 more
core   +3 more sources

Fluid and Neuroimaging Biomarkers in Microgliopathy Colony‐Stimulating Factor‐1 Receptor‐Related Disorders

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aims to identify both fluid and neuroimaging biomarkers for CSF1R‐RD that can inform the optimal timing of treatment administration to maximize therapeutic benefit, while also providing sensitive quantitative measurements to monitor disease progression.
Tomasz Chmiela   +13 more
wiley   +1 more source

Buy a home or rent? A better way to choose [PDF]

open access: yes
Knowing whether buying a home is a better financial move for a family than renting requires a consideration of costs and options that people often neglect to factor in.
Ozgur Emre Ergungor, Saeed Zaman
core  

Exploratory Analysis of ELP1 Expression in Whole Blood From Patients With Familial Dysautonomia

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Familial dysautonomia (FD) is a hereditary neurodevelopmental disorder caused by aberrant splicing of the ELP1 gene, leading to a tissue‐specific reduction in ELP1 protein expression. Preclinical models indicate that increasing ELP1 levels can mitigate disease manifestations.
Alejandra González‐Duarte   +13 more
wiley   +1 more source

Information in T-bill Auction Bid Distributions [PDF]

open access: yes
In this paper UK data is used to compare two potential sources of information regarding market uncertainty about future short interest rates. One is the so-called risk-neutral density function (RND) derived from interest rate option prices, the other is ...
Attila Csajbók
core  

Exploring sensor data management [PDF]

open access: yes, 2006
The increasing availability of cheap, small, low-power sensor hardware and the ubiquity of wired and wireless networks has led to the prediction that `smart evironments' will emerge in the near future.
Evers, Sander
core   +2 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein   +7 more
wiley   +1 more source

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