Results 91 to 100 of about 25,109,469 (289)
Information technology and business value: How complementary IT usage platform and capable resources explain IT business value variation [PDF]
, 2008 Understanding information technology’s (ITs) contribution to business value is an imperative issue, and while we have attempted to untangle the relationship between IT and business value with some success, our knowledge of specific factors leading to ITs
Heales, J. +3 more
core +1 more source
The value of implementation and the value of information: combined and uneven development [PDF]
, 2008 <i>Aim</i>: In a budget-constrained health care system, the decision to invest in strategies to improve the implementation of cost-effective technologies must be made alongside decisions regarding investment in the technologies themselves and
Elisabeth Fenwick +5 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Журнал нано- та електронної фізикиThe article is devoted to a comprehensive approach to predicting the heat resistance of plasticized epoxy nanocomposites. The aim of the study was to apply ensemble machine learning algorithms to identify key mechanical factors in predicting the heat ...
O. Pastukh +6 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
The Kansas Information Technology Architecture
, 2009 Version 11.2; application/pdf; Cover title.; "12/28/2009."; "This Architecture provided to the State of Kansas by the Kansas Technical Architecture Review Board (KTARB), presented to and approved by the Information Technology Executive ...
Kansas. Information Technology Office.
core
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
The value of information and the value of awareness [PDF]
Theory and Decision, 2015 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +6 more sources
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source