Results 111 to 120 of about 25,109,469 (289)
STIF: Intuitionistic fuzzy Gaussian membership function with statistical transformation weight of evidence and information value for private information preservation. [PDF]
Distrib Parallel Databases, 2023 Kumar GS, Premalatha K.
europepmc +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
A patient-centered gout information value chain: a scoping review. [PDF]
Patient Educ Couns, 2022 Russell MJ, Kim S, Lenert A.
europepmc +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Use of Machine Learning to Determine the Information Value of a BMI Screening Program. [PDF]
Am J Prev Med, 2021 Zare S, Thomsen MR, Nayga RM, Goudie A.
europepmc +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Disease Surveillance Investments and Administration: Limits to Information Value in Pakistan Polio Eradication. [PDF]
Risk Anal, 2021 Scott RP, Cullen AC, Chabot-Couture G.
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Geomatics, Natural Hazards & RiskLandslide susceptibility assessment and attribution analysis of triggering factors are essential for regional risk management. However, existing methods face challenges such as subjectivity in determining factor weights and insufficient capacity to ...
Yilin Zhu +6 more
doaj +1 more source