Results 121 to 130 of about 13,293,967 (299)

Landslide susceptibility assessment and attribution analysis in Yunnan Province based on weighted information value-logistic regression model

Geomatics, Natural Hazards & Risk
Landslide susceptibility assessment and attribution analysis of triggering factors are essential for regional risk management. However, existing methods face challenges such as subjectivity in determining factor weights and insufficient capacity to ...
Yilin Zhu, Shuangyun Peng, Zhiqiang Lin, Bangmei Huang, Ting Li, Rui Zhang, Rong Jin   +6 more
doaj   +1 more source

Congestion, risk aversion and the value of information [PDF]

Information about traffic conditions is conveyed to drivers by radio and variable message signs, and more recently available via the Internet and Advanced Traveler Information Systems (ATIS).
André de Palma, Nathalie Picard, Robin Lindsey   +2 more
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

GIS-based landslide susceptibility assessment using a random forest model: a case study of Ganzi and Aba, China

Geomatics, Natural Hazards & Risk
Landslides pose a significant threat to human life and regional development in Ganzi and Aba Prefectures due to their complex topography. Therefore, this paper aims to enhance landslide hazard prevention by conducting assessment and landslide ...
Ying Zhou, Lu Zhang, Yuan Feng, Xinyun Zhang, Haowen Liu, Junxi Li, Wei Wei   +6 more
doaj   +1 more source

The Value of Online Information Privacy: An Empirical Investigation [PDF]

Concern over online information privacy is widespread and rising. However, prior research is silent about the value of information privacy in the presence of potential benefits from sharing personally identifiable information.
I.P.L. Png, Il-Horn Hann, Kai-Lung Hui, Tom S. Lee   +3 more
core  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Data Analysis Methodology Utilizing the Statistical Metrics Weight of Evidence (WoE) and Information Value (IV) to Assist in Asset Management of Power Transformers

IEEE Access
This article proposes an original contribution to assist in evaluating the condition of power transformers, the main asset of the electrical energy transmission sector. Due to constructive similarity, reactors are also evaluated. Data from the insulating
Gabriela S. Rema, Rafael M. Soares, Benedito D. Bonatto, Antonio C. S. Lima   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source