Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Exploring the impact of a pain assessment information visualization tool on provider-patient pain discussion with limited English proficiency Hmong patients. [PDF]
Lor M, Yang MN, Brown R, Chewning B.
europepmc +1 more source
Engaging Patients With Advance Directives Using an Information Visualization Approach. [PDF]
Woollen J, Bakken S.
europepmc +1 more source
Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Information Retrieval across Information Visualization.
This article presents the analytical and retrieval potential of visualization maps. Obtained maps were tested as information retrieval (IR) interface. The collection of documents derived from the ACM Digital Library was mapped on the sphere surface. Proposed approach uses nonlinear similarity of documents by comparing ascribed thematic categories and ...
Bala, Piotr +2 more
openaire +2 more sources
Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley +1 more source
Surface Glyphs for Efficient Visualization of Multivariate Data
We present a first effort to evaluate the possible utility of a new type of surface glyphs intended for visualizations of multivariate spatial data.
Forsell, C., Seipel, Stefan,, Lind, M.
core
Geographic information system and information visualization capacity building: Successful polio eradication and current and future challenges in the COVID-19 era for the World Health Organization's African region. [PDF]
Kipterer JK +10 more
europepmc +1 more source
Innovative information visualization of electronic health record data: a systematic review. [PDF]
West VL, Borland D, Hammond WE.
europepmc +1 more source
Evolution‐guided yeast complementation reveals functional differences in human PSPH variants
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez +6 more
wiley +1 more source

