Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai +8 more
wiley +1 more source
Exploring the impact of a pain assessment information visualization tool on provider-patient pain discussion with limited English proficiency Hmong patients. [PDF]
Lor M, Yang MN, Brown R, Chewning B.
europepmc +1 more source
Engaging Patients With Advance Directives Using an Information Visualization Approach. [PDF]
Woollen J, Bakken S.
europepmc +1 more source
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley +1 more source
Geographic information system and information visualization capacity building: Successful polio eradication and current and future challenges in the COVID-19 era for the World Health Organization's African region. [PDF]
Kipterer JK +10 more
europepmc +1 more source
Information Retrieval across Information Visualization.
This article presents the analytical and retrieval potential of visualization maps. Obtained maps were tested as information retrieval (IR) interface. The collection of documents derived from the ACM Digital Library was mapped on the sphere surface. Proposed approach uses nonlinear similarity of documents by comparing ascribed thematic categories and ...
Bala, Piotr +2 more
openaire +2 more sources
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Innovative information visualization of electronic health record data: a systematic review. [PDF]
West VL, Borland D, Hammond WE.
europepmc +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
Effects of Information Visualization on Older Adults' Decision-Making Performance in a Medicare Plan Selection Task: A Comparative Usability Study. [PDF]
Price MM +3 more
europepmc +1 more source

