Results 51 to 60 of about 1,261,383 (268)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Simultaneous Generation of Multiple Three-Dimensional Tractor Curve Beams

open access: yesNanoscale Research Letters, 2019
A tractor beam, which has the ability to attract objects, is a class of special optical beams. Currently, people are using the holographic technology to shape complex optical tractor beams for both fundamental research and practical applications. However,
Jun Wu, Xinquan Tang, Jun Xia
doaj   +1 more source

Dynamic Spectral Modulation on Meta‐Waveguides Utilizing Liquid Crystal

open access: yesAdvanced Science, 2023
The integration of metasurfaces and optical waveguides is gradually attracting the attention of researchers because it allows for more efficient manipulation and guidance of light.
Chengkun Dong   +13 more
doaj   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

Characterization and Optimization of Field of View in a Holographic Waveguide Display

open access: yesIEEE Photonics Journal, 2017
The paper presents the characterization of the field of view (FOV) in a holographic waveguide display (HWD) with a broadband spectrum image source. The influences of parameters such as grating slanted angle of volume holographic grating (VHG), grating ...
Zhongwen Shen   +3 more
doaj   +1 more source

Information Visualization and Design

open access: yesProceedings of the 11th International Symposium on Visual Information Communication and Interaction, 2018
Recently, there has been an increase of data visualizations and in the diversity of forms. In parallel, design research has developed over the last decades. However, there have been few academic publications in the area of design specifically focusing on visualization research.
Fagerholm, Anna-Sara, Andersson, Mattias
openaire   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Real-Time Electro-Optical Tunable Hyperlens Under Subwavelength Scale

open access: yesIEEE Photonics Journal, 2018
Hyperlens consisted by period plasmonic metamaterials is an interesting technology for the optical imaging of arbitrary objects beyond the diffraction limit in the far field, which has great potential applications in nanophotonics.
Dan Su   +8 more
doaj   +1 more source

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