Results 81 to 90 of about 14,095,467 (307)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Information Visualization and Design
Proceedings of the 11th International Symposium on Visual Information Communication and Interaction, 2018 Recently, there has been an increase of data visualizations and in the diversity of forms. In parallel, design research has developed over the last decades. However, there have been few academic publications in the area of design specifically focusing on visualization research.
Fagerholm, Anna-Sara, Andersson, Mattias
openaire +4 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Information Visualization Of An Agent-Based Financial System Model [PDF]
This paper considers the application of information visualization techniques to an agent-based model of a financial system. The minority game is a simple agent-based model which can be used to simulate the events in a real-world financial market.
Wei Jiang +1 more
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Information Services and Use, 2016 Information is only valuable when it can be found. It is relatively easy to find information that we know exists; you just need to know what you want to find, where to look for it, and how to express yourself. It might require a little effort to find it, but this work is usually rewarded.
openaire +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
, 2007 International audienceFrom May 28 to June 1, 2007, a seminar on "Information Visualization - Human-Centered Issues in Visual Representation, Interaction, and Evaluation" took place at the International Conference and Research Center for Computer Science,
Kerren, Andreas, +6 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Visualization for the masses : learning from the experts [PDF]
, 2010 18th International Conference on Case-based Reasoning (ICCBR 2010), 19-22 July 2010, Alessandria, ItalyIncreasingly, in our everyday lives, we rely on our ability to access and understand complex information.
Jill Freyne +3 more
core +1 more source