Results 81 to 90 of about 17,216,616 (299)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Information Visualization Of An Agent-Based Financial System Model [PDF]
This paper considers the application of information visualization techniques to an agent-based model of a financial system. The minority game is a simple agent-based model which can be used to simulate the events in a real-world financial market.
Wei Jiang +1 more
core
International audienceFrom May 28 to June 1, 2007, a seminar on "Information Visualization - Human-Centered Issues in Visual Representation, Interaction, and Evaluation" took place at the International Conference and Research Center for Computer Science,
Kerren, Andreas, +6 more
core +1 more source
Information is only valuable when it can be found. It is relatively easy to find information that we know exists; you just need to know what you want to find, where to look for it, and how to express yourself. It might require a little effort to find it, but this work is usually rewarded.
openaire +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Visualization of Financial Information
This paper has the intention to present new ideas for data mining and visualization of financial information. On this occasion, new methods for graphical representaton of abstract and multi-dimensional information and information structures are discussed.
Lux, M.
core +1 more source
The effect of plasmon-induced hot carriers (HCs) enables the possibility of applying semiconductors with wide band gaps to visible light catalysis, which becomes an emerging research field in environmental protections.
Tong Zhang +7 more
doaj +1 more source

