Results 101 to 110 of about 107,894 (308)

Informational Model of Consciousness: From Philosophic Concepts to an Information Science of Consciousness [PDF]

open access: yes, 2019
On the long and well-worn road of many, but justifiable attempts of human to discover his origin, his trajectory as a species, and a suitable understanding consciousness, his system allowing the connection to the environment and to ...
Gaiseanu, Florin
core  

Future Community-Based Ecotourism (CBET) development [PDF]

open access: yes, 2020
Ecotourism is an alternative form of tourism and is usually confused with natural and cultural tourism.CBET is fast becoming a popular biodiversity conservation tool that develops and benefits the local community.
Ibrahim, B.   +4 more
core  

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

open access: yesFEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde   +3 more
wiley   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

NEW METHODOLOGIES AND TENDENCIES IN QUALITATIVE MARKETING RESEARCH [PDF]

open access: yes
: In this paper we will approach another qualitative marketing research type based ona new relation ââ¬â from laboratory to reality . In fact believe and do not research is an oldsaying stepped out of the marketing specialists’ vocabulary. The increased
Arcadie Hinescu, Ionela Gavrila-Paven
core  

Complexity, BioComplexity, the Connectionist Conjecture and Ontology of Complexity\ud [PDF]

open access: yes, 2009
This paper develops and integrates major ideas and concepts on complexity and biocomplexity - the connectionist conjecture, universal ontology of complexity, irreducible complexity of totality & inherent randomness, perpetual evolution of information,
Mukherjee, Mr. Debaprasad
core  

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

TEACHING METHODOLOGY OF INFORMATION SYSTEMS

open access: yesProceedings of the 4th International Conference on Computer Supported Education, 2012
The article describes the content and methodology of teaching the foundations of information systems development. It presents the content and structure of the course, motivational aspects applied, and an illustrative example of a credit assignment - the result of student's work.
openaire   +3 more sources

VULNERABILITY AND E-CRIMINALITY OF IT [PDF]

open access: yes
The development of an informational society requires consolidating trust in information and communication technology (ICT), the protection of personal data and of the right to a private life, but also promoting a world and national unification of the ...
MARES Marius Daniel, MARES Valerica
core  

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

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