Results 91 to 100 of about 107,894 (308)

Graphic Design and Speech Therapy: an interuniversity and transdisciplinary proposal aimed at inclusive graphic design solutions

open access: yesProjetica, 2016
This article aims to present the inter-university and transdisciplinarity partnership between Graphic Design and Speech Therapy to produce innovative research methodologies and project in inclusives materials that take into account the communication ...
Cassia Leticia Carrara Domiciano   +1 more
doaj   +1 more source

New Valences for the Financial-Accounting System [PDF]

open access: yes
A new approach to a company’s information systems is needed, if we take into consideration the globalization process of the economy, the intensified competition, the impose of new qualitative demands or the adjustment to new accounting standards.
Adrian LUPASC   +2 more
core  

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Human dimensions of global environmental change: A review of frameworks and research gaps. [PDF]

open access: yes, 2005
This review of current knowledge in, and development of, priorities for research into the human dimensions of global environmental change has been conducted to assist the Foundation for Research Science and Technology to formulate their research needs ...
Campbell, John   +3 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Distributed Transcripts for Online Learning: Design Issues

open access: yesJournal of Interactive Media in Education, 2001
: A set of guiding principles is stated for the development of standards for representing student educational assessment information. These principles support the learner, rather than the academic institution, as the focus of an information system ...
Steven L. Tanimoto
doaj   +1 more source

Information society policies 2.0: a critical analysis of the potential and pitfalls of social computing & informatics in the light of e-inclusion [PDF]

open access: yes, 2010
In this paper we reflect on how research and policies can and/or should help in the development of a sustainable information society for all. More specifically, we critically investigate how social computing & informatics can entail both potential and ...
Verdegem, Pieter
core   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

Transforming Organisational Culture through the Impact of Information Integration [PDF]

open access: yes
Over the last 2-3 decades, investments in the new information technology (NIT) have left a deep impression on the life of organisations, that goes beyond ample differences in each organisation’s degree of automatisation.
Doina FOTACHE, Magdalena DANILET
core  

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