Results 81 to 90 of about 107,894 (308)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Towards an understanding of corporate web identity [PDF]
, 2014 No abstract ...
Elliott, C., Robinson, S.
core
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Gestão & Produção, 2010 Este artigo compreende as etapas iniciais do Processo de Desenvolvimento de Produtos - mais especificamente a fase conhecida como Projeto Informacional -, considerando-as fundamentais para o sucesso de um novo produto no mercado.
Elton Moura Nickel +4 more
doaj +1 more source
The process of knowledge acquisition through interpersonal communication in the "Parents as first teachers" programme : a thesis presented in partial fulfilment of the requirements for the degree of Master of Management in Communication Management at Massey University [PDF]
, 2001 Communication researchers interested in the role played by knowledge in social terms have produced a variety of explorations in recent times of "knowledge gaps" and informational inequities between various groups in society.
Williams, Jocelyn Elizabeth
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Subconscious responses to fear-appeal health warnings: An exploratory study of cigarette packaging
South African Journal of Economic and Management Sciences, 2017 Background: Tobacco smoking has serious health and financial implications for both smokers and non-smokers. A wide range of measures have been used over many years to combat this scourge. One of these measures is social marketing communication campaigns.
Christo Boshoff, Lucea Toerien
doaj +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source