Results 41 to 50 of about 28,038 (289)

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

Press Freedom, Corporate Governance and Stock Price Informativeness

open access: yes, 2022
Purpose of the study • To examine the relationship between corporate governance mechanisms (firm-level transparency, product market competition, and financial leverage) and stock price informativeness.
Ng, Tuan Hock   +2 more
core   +1 more source

Studying the Effect of Corporation’s Disclosure Quality Rank on Income-Smoothing and Informativeness of Tehran Stock Exchange’s Listed Companies [PDF]

open access: yesIranian Journal of Finance, 1999
The study is to review the disclosure quality rank on income-smoothing and informativeness by means of four hypotheses. The timescale is between 2010 and 2016, and 149 TSE’s listed companies are studied. The first hypothesis examines the effect of higher
Heidar Foroughnejad   +2 more
doaj   +1 more source

Accuracy-Informativeness Tradeoff for Interval Forecast Comparison [PDF]

open access: yes, 2019
Price interval forecasts are analyzed in this study focusing on three main characteristics: coverage, error and informativeness. The tradeoff between accuracy and informativeness results from the fact that greater accuracy is achieved at the cost of ...
Mattos, Fabio, Isengildina, Olga
core   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

open access: yesMolecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński   +12 more
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Metonymy and frame integration: Interfacing between concepts and discourse

open access: yesTopics in Linguistics, 2019
This article inquiries into specific aspects of the relation between conceptual contiguity found in metonymic shifts and the online construction of frames, seen as a dynamic process of construal.
Ioannou Georgios
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

open access: yesFEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova   +2 more
wiley   +1 more source

Bet-on agreements and stock price informativeness

open access: yes
Betting agreements, with their growing popularity in enterprises, may profoundly affect a firm's information environment. Using a sample of publicly listed firms in China from 2011 to 2021, this study explores the effect of betting agreements and stock ...
Wu, JianHan, Zhao, Zhenzhen, Li, Yuanqi
core   +3 more sources

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