Results 81 to 90 of about 628,593 (200)

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, Volume 13, Issue 41, 22 July 2026.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

The biphasic role of the infrapatellar fat pad in osteoarthritis

Biomedicine & Pharmacotherapy
Osteoarthritis (OA) is a progressive degenerative disease resulting in joint deterioration. It is a whole organ disease characterized by cartilage degeneration and varying degrees of synovitis, involving pathological changes in all joint tissues, such as cartilage, subchondral bone, ligaments, meniscus, synovium, and infrapatellar fat pad (IPFP).
Songkai, Yue, Ganggang, Zhai, Siyu, Zhao, Xiaming, Liang, Yunke, Liu, Jia, Zheng, Xiaoyang, Chen, Yonghui, Dong   +7 more
openaire   +2 more sources

Tumors and tumor-like lesions of infrapatellar fat pad and surrounding tissues: A review of the literature

, 2018
The infrapatellar fat pad (IFP) is an intracapsular structure with critical importance both mechanically and endocrinologically. Its dysfunction must be considered while clinically investigating the symptoms arising from the knee joint. Infrapatellar fat
Erdem Aras SEZGİN and O. Şahap ATİK, Sezgin, Erdem Aras and Atik, O. Sahap   +1 more
core   +2 more sources

Broken-fat pad sign: a characteristic radiographic finding to distinguish between knee rheumatoid arthritis and osteoarthritis

Insights into Imaging
Objectives Diagnostic imaging plays an important role in the pre-treatment workup of knee osteoarthritis (OA) and rheumatoid arthritis (RA). Herein, we identified a useful MRI sign of infrapatellar fat pad (IPFP) to improve diagnosis.
Qizheng Wang, Weili Zhao, Xiaoxi Ji, Yongye Chen, Ke Liu, Yupeng Zhu, Ruixin Yan, Siyuan Qin, Peijin Xin, Ning Lang   +9 more
doaj   +1 more source

Osteoarthritis: Epidemiology, Diagnosis, and Treatment

MedComm, Volume 7, Issue 7, July 2026.
Osteoarthritis (OA) is a multifactorial degenerative joint disease and a leading cause of disability worldwide. This graphical abstract summarizes the epidemiology, diagnostic strategies, and therapeutic approaches of OA. OA development is driven by aging, metabolic dysregulation, and mechanical stress, leading to progressive joint degeneration ...
Qin Ru, Dongliang Yuan, Shide Jiang, Xiaoxuan Zhao, Xu Liu, Yusheng Li, Shuguang Liu, Yuxiang Wu   +7 more
wiley   +1 more source

The normal arthroscopic anantomy of the infrapatellar fat pad

, 2003
The Normal Arthroscopic Anatomy of the Infrapatellar Fat Pad. Aims: To define the normal arthroscopic anatomy of the infrapatellar fat pad and any common variations.
Brooker, B., Morris, H., Brukner, P. D.
core  

Para-articular osteochondroma of the infrapatellar fat pad

International Journal of Surgery Case Reports, 2020
Abstract Introduction Para-articular osteochondromas are not very common. We performed simple marginal excision for three cases. Presentation of case We encountered three cases of para-articular osteochondroma of the ...
Nishimura, Takahiro, Saku, Isaku, Kanda, Shotaro, Fukushima, Takashi, Akiyama, Toru   +4 more
openaire   +2 more sources

Infrapatellar Fat Pad-Derived Stem Cell-Based Regenerative Strategies in Orthopedic Surgery

, 2018
Infrapatellar fat pad is a densely vascularized and innervated extrasynovial tissue that fills the anterior knee compartment. It plays a role in knee biomechanics as well as constitutes a source of stem cells for regeneration after knee injury ...
Yilgor Huri, Pinar
core   +1 more source

Synovial hemangioma of infrapatellar (Hoffa) fat pad: Magnetic resonance imaging and ultrasound features [PDF]

, 2016
The infrapatellar fat pad (IFP) also known as Hoffa fat pad, an intracapsular extrasynovial structure readily visualized on magnetic resonance imaging of the knee,1 can be affected by a variety of pathologic conditions (lipoma, hemangioma, synovial ...
STRAMARE, ROBERTO, ROMANUCCI, GIOVANNA, BELTRAME, VALERIA, Zulian, Francesco   +3 more
core   +1 more source

The nature of anterior knee pain following injection of hypertonic saline into the infrapatellar fat pad

, 2004
The infrapatellar fat pad has been implicated as a possible source of anterior knee pain. This study examined the nature, distribution and time-course of experimentally induced pain in the infrapatellar fat pad.
Mellor, R., Souvlis, T., Bennell, K., Hodges, P., Bexander, C.   +4 more
core   +1 more source