Results 71 to 80 of about 6,036 (219)

Osteoarthritis: Epidemiology, Pathogenesis, and Treatment

MedComm, Volume 7, Issue 4, April 2026.
Osteoarthritis is a prevalent degenerative joint disease with a growing global burden. Its development involves complex interactions among epidemiological factors, pathological changes, molecular signaling, and epigenetic regulation. Understanding these mechanisms provides insights into disease progression and supports the development of therapeutic ...
Tianrui Chen, Wenlong Chen, Tianpeng Xu, Hong Wang, Yuheng Zhang, Li Wang, Sijie Zhu, Huaqiang Tao, Xing Yang   +8 more
wiley   +1 more source

The equine patellar ligaments and the infrapatellar fat pad – a microanatomical study

BMC Veterinary Research, 2023
Background Interpretation of patellar ligament (PL) ultrasonography may be difficult, as hypoechoic or heterogenous echogenicity are common findings.
Cathrine Taule Fjordbakk, Patrick Marques-Smith   +1 more
doaj   +1 more source

Comparison of fatty-acid-binding protein 4 and adiponectin levels in infrapatellar fat pad and subcutaneous adipose tissue, synovial fluid and plasma in subjects with knee osteoarthritis [PDF]

, 2013
Conference Theme: Defying the Aging Spine: Our Mission ContinuesConcurrent Free Papers 2 - Basic Science/General Orthopaedics: no. 2.8Introduction: It was recently reported that inflammation is involved in the pathogenesis of osteoarthritis (OA ...
Chiu, KY, Li, T, Song, YQ, Xu, AM, Yan, CH   +4 more
core  

Evaluation, Treatment, and Rehabilitation Implications of the Infrapatellar Fat Pad [PDF]

Sports Health: A Multidisciplinary Approach, 2015
Context: The infrapatellar fat pad (IFP) is in the anterior knee compartment and may be a major pain generator. Evidence Acquisition: A PubMed database search using the terms Hoffas fat pad, anterior interval, and infrapatellar fat pad was performed from the years 1970 to 2015. Study Design: Clinical review. Level of Evidence: Level 5. Results: Limited
Hannon, Joseph, Bardenett, Sean, Singleton, Steven, Garrison, J. Craig   +3 more
openaire   +2 more sources

Spatial Transcriptomics of TMJ Reveals a Remodeling Fibroblast‐Immune Microenvironment Driving Arthritis Pain

Advanced Science, Volume 13, Issue 18, 27 March 2026.
Spatial transcriptomics reveals a remodeled fibroblast‐immune microenvironment in the temporomandibular joint (TMJ) during arthritis. By combining seqFISH with genetic mouse models, this study uncovers TMJ spatial cell atalas, macrophage‐fibroblast crosstalk, and cytokine signaling pathways driving TMJ inflammation and pain.
Ziying Lin, Supawadee Jariyasakulroj, Yang Shu, Jingyi Chen, Qing Chang, Pao‐Fen Ko, Yuyueyang Qiu, Feixiang Chen, David Ahn, Zhen Zhao, Jian‐Fu Chen   +10 more
wiley   +1 more source

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

Advanced Science, Volume 13, Issue 7, 3 February 2026.
The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang, Yi Liu, Ziying Sun, Jia Li, Zhihao Lu, Jiayuan Huang, Shixian Hu, Peihua Cao, Xiaolong Cao, Shangru Li, Jianzhao Ruan, Jinhui Liu, Jingyu Xie, Haitao Sun, Tianyu Chen, Shengfa Li, Zhaohua Zhu, Zhibo Wen, Rocky S. Tuan, David John Hunter, Zhong Alan Li, Dongquan Shi, Changhai Ding   +22 more
wiley   +1 more source

A novel infrapatellar approach of ultrasound-guided intra-articular injection of the knee from both lateral and medial side: a case series

Therapeutic Advances in Musculoskeletal Disease, 2023
Knee osteoarthritis (OA) is common. Ultrasound-guided intra-articular injection (UGIAI) using the superolateral approach is currently the gold standard for treating knee OA, but it is not 100% accurate, especially in patients with no knee effusion ...
King Hei Stanley Lam, Yung-Tsan Wu, Kenneth Dean Reeves, Admir Hadzic, Mario Fajardo Perez, Sau Nga Fu   +5 more
doaj   +1 more source

Fast 3D UTE in vivo T1 and T2*$$ {\mathrm{T}}_2^{\ast } $$ mapping of fast relaxing knee tissues at 3 T

Magnetic Resonance in Medicine, Volume 95, Issue 2, Page 693-705, February 2026.
Abstract Purpose UTE MR imaging captures quantitative signals in fast‐relaxing tissues, enabling anatomical visualization and quantitative assessment of T1 and T2*$$ {\mathrm{T}}_2^{\ast } $$ relaxation times. However, the clinical application of quantitative UTE MRI is limited by long acquisition times.
Maik Rothe, Selina Riedel, Anne Slawig, Andreas Deistung, Klaus Bohndorf, Richard Brill, Walter A. Wohlgemuth, Alexander Gussew   +7 more
wiley   +1 more source

Intra-articular injections of mesenchymal stem cells for knee osteoarthritis [PDF]

, 2014
Este artículo está disponible en la página web de la revista: http://www.amjorthopedics.comKnee osteoarthritis (KOA) represents an enormous societal burden.
Rodríguez Merchán, E. Carlos
core   +1 more source

Radiographic assessment of popliteal sesamoid position and cranial tibial subluxation in canine stifle joints undergoing TPLO: A retrospective study of 163 dogs

Veterinary Surgery, Volume 55, Issue 2, Page 317-326, February 2026.
Abstract Objective To determine the prevalence of popliteal sesamoid displacement (PSD) in dogs with cranial cruciate ligament disease (CCLD) on radiographs, assess its reduction following tibial plateau leveling osteotomy (TPLO), and evaluate cranial tibial subluxation (CTS) pre‐ and postoperatively.
Pierre P. Picavet, Theo Corbarieu, Darby Toth, Alexandre Thibault, Justine Monseur, Walter Renberg, James K. Roush, Martin Hamon   +7 more
wiley   +1 more source