Results 51 to 60 of about 3,545,696 (359)

Uncovering a high-performance bio-mimetic cellular structure from trabecular bone

Scientific Reports, 2020
The complex cellular structure of trabecular bone possesses lightweight and superior energy absorption capabilities. By mimicking this novel high-performance structure, engineered cellular structures can be advanced into a new generation of protective ...
Abdallah Ghazlan, Tuan Ngo, Tuan Nguyen, Steven Linforth, Tu Van Le   +4 more
doaj   +1 more source

Hercules finances research infrastructure [PDF]

, 2009
In 2007 the Flemish government created a structural funding channel to support investment in research infrastructure: Hercules. On 15 October 2008 the Hercules Foundation approved a first list of investment proposals. In this article specific features of
Vanden Berghe, Jeroen
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Arch dam point cloud segmentation based on deep feature learning and normal vector data optimization

Scientific Reports
Separating the dam body, spillway, and other structures from the point cloud in the dam area is an important step in dam deformation monitoring. Manual segmentation is time consuming and inaccurate.
Huokun Li, Yuekang Li, Yijing Li, Weichao Lu, Zhixing Zhu, Teng Feng, Bo Liu   +6 more
doaj   +1 more source

Developing an e-infrastructure for social science [PDF]

, 2007
We outline the aims and progress to date of the National Centre for e-Social Science e-Infrastructure project. We examine the challenges faced by the project, namely in ensuring outputs are appropriate to social scientists, managing the transition from
Allan, Rob, Baird, Kenny, Birkin, Mark, Crouchley, Rob, Daw, Michael, de la Flor, Grace, Dutton, William H., Edwards, Pete, Hewitt, T., Jie, Wei, Jirotka, Marina, Lin, Yuwei, Miller, Ken, Procter, Rob, Schroeder, Ralph, Turner, A., Voss, Alex, Yang, Xiaobo   +17 more
core  

Future direction for infrastructure research [PDF]

, 2017
Infrastructure was not a widely researched topic until Aschauer identified the wider economic benefits of investment in the United States during the 1980s.
Regan, Michael
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Recent advances and current landscape of software tools for image analysis and dosimetry in nuclear medicine

EJNMMI Physics
Recent advancements in nuclear medicine, particularly in personalised radiopharmaceutical therapy, have emphasised the growing need for precise assessments of therapeutic safety and efficacy.
Kaluzi Banda, Milani Qebetu, Pryaska Goorhoo, Khomotso Legodi, Johannes van Staden, Mike Sathekge, Keamogetswe Ramonaheng   +6 more
doaj   +1 more source

Research on Seismic Performance of Frame Structure with Beam Staircases

Buildings, 2022
Beam staircases are widely used in frame structures. In structural design, stair flights are often ignored in the model establishment, and their loads are only added to the stair beams.
Ming Wen, Hongxiang Tian, Weiwei Wang, Baokui Chen, Huayao Fu   +4 more
doaj   +1 more source

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source