Results 61 to 70 of about 626,696 (266)

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

ARCHITECTURAL AND STRUCTURAL AND FUNCTIONAL FEATURES OF THE ORGANIZATION OF PARALLEL-HIERARCHICAL MEMORY

Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska
Parallel hierarchical memory (PI memory) is a new type of memory that is designed to improve the performance of parallel computing systems. PI memory is composed of two blocks: a mask RAM and a tail element RAM.
Leonid Timchenko, Natalia Kokriatska, Volodymyr Tverdomed, Iryna Yepifanova, Yurii Didenko, Dmytro Zhuk, Maksym Kozyr, Iryna Shakhina   +7 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

An Equivalent Model for Cooling Tower Boundary Conditions in Industrial Recirculating Cooling Water Systems

Energies
To mitigate the risks of pressure surges and water hammer during accidental pump trips in industrial cooling water systems, accurate boundary modeling of cooling towers is essential. This study employs the Method of Characteristics (MOC) to evaluate four
Wei Huang, Yucong Chen, Huokun Li, Zhongzheng He, Zhe Li, Bo Liu, Gang Wang   +6 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

Response of nitrogen emissions to land use changes and driving forces analysis in Jiangxi province under multiple scenarios

Scientific Reports
In recent decades, accelerated economic growth has positioned non-point source pollution as a critical threat to China’s ecological security. Jiangxi Province, a pivotal ecological barrier in the middle-lower Yangtze River Basin, confronts escalating ...
Chun Fu, Libin Xiang, Yezhong Liu, Tianming Zhou   +3 more
doaj   +1 more source

Bridges and Infrastructure

Docomomo Journal, 2011
At present, it is by no means an exaggeration to say that innumerable bridges and infrastructures are able to bring us to the end of the earth, whether these are monuments, scattered in a remote area, recognized or not. situated where mankind intensively has made its effort to extend daily circles of life till the present day.
Kyo Takenouchi, Ola Wedebrunn
openaire   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Money as Infrastructure

SSRN Electronic Journal, 2017
Traditional infrastructure regulation–the law of regulated industries–rests atop three pillars: rate regulation, entry restriction, and universal service. This mode of regulation has typically been applied to providers of network-type resources: resources that are optimally supplied as integrated systems.
openaire   +2 more sources