Results 21 to 30 of about 239,843 (294)

WHAT IS THE PRICE FOR BREAKING EU LAW? [PDF]

open access: yesChallenges of the Knowledge Society, 2017
Financial sanctions, as lump sum and penalty payments, can be imposed to Member States that failed to implement a judgement establishing an infringement.
Ioana-Mihaela DIMITRIU
doaj  

Case Law: A Review of Selected Pharmaceutical Patents in the UK Courts During 2020

open access: yesBritish Journal of Pharmacy, 2021
Patents lie at the interface between technology and law. This article provides a critical review of four high profile cases from 2020 in which patents relating to pharmaceuticals were litigated in the UK Courts. The selected cases in this review involved
Sarah-Jane Crawford   +2 more
doaj   +1 more source

Nový postup EU pro posílení právního státu

open access: yesČasopis pro Právní Vědu a Praxi, 2016
Článek pojednává o novém postupu Evropské unie pro posílení právního státu. Tento nově navrhovaný mechanismus je nejprve srovnáván s jinými dosavadními mechanismy pro prosazování unijního práva. Zkoumán je přitom jak z pohledu právního, tak i politického.
David Sehnálek
doaj   +1 more source

Don\u27t Confuse Metatags with Initial Interest Confusion [PDF]

open access: yes, 2002
This Comment focuses on whether the legal doctrine of initial interest confusion should be applied in metatag related trademark infringement cases. The Comment agues that because initial interest confusion does not improve or clarify the existing ...
Dunaevsky, Yelena
core   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

THE LIMITS OF RECOURSE TO FORCE IN THE CONTEXT OF CONTEMPORARY GEOPOLITICS [PDF]

open access: yesChallenges of the Knowledge Society, 2019
Recourse to force represents a highly controversial subject matter, given its political sensitivity, as well as the legal framework that authorizes it.
Sandra Sophie-Elise OLĂNESCU
doaj  

Willful Infringement and the Evidentiary Value of Opinion Letters After Knorr–Bremse v. Dana [PDF]

open access: yes, 2005
Recently, the Federal Circuit in Knorr-Bremse v. Dana overruled almost twenty years of precedent by striking down the adverse inference doctrine, which had created a negative presumption against any alleged patent infringer for failing to obtain and ...
Stowell, Joshua
core   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

open access: yesFEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui   +10 more
wiley   +1 more source

The Doctoral Student’s Responsibility for Violation of Ethical Standards During Doctoral Studies

open access: yesEIRP Proceedings, 2022
Intellectual property law enjoys the most expansive and branching evolution of the last century, both in terms of national regulations and in terms of signed international conventions and adopted Community directives, as evidenced even by established ...
Maria Cristiana Ieremie
doaj  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

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