Results 21 to 30 of about 12,156 (243)
WHAT IS THE PRICE FOR BREAKING EU LAW? [PDF]
Financial sanctions, as lump sum and penalty payments, can be imposed to Member States that failed to implement a judgement establishing an infringement.
Ioana-Mihaela DIMITRIU
doaj
Case Law: A Review of Selected Pharmaceutical Patents in the UK Courts during 2021
Patents lie at the interface between technology and law. This review provides a summary of four high-profile cases from 2021 in which patents in the pharmaceutical or medical space were litigated in the UK Courts.
Sarah-Jane Crawford +2 more
doaj +1 more source
Nový postup EU pro posílení právního státu
Článek pojednává o novém postupu Evropské unie pro posílení právního státu. Tento nově navrhovaný mechanismus je nejprve srovnáván s jinými dosavadními mechanismy pro prosazování unijního práva. Zkoumán je přitom jak z pohledu právního, tak i politického.
David Sehnálek
doaj +1 more source
Case Law: A Review of Selected Pharmaceutical Patents in the UK Courts During 2020
Patents lie at the interface between technology and law. This article provides a critical review of four high profile cases from 2020 in which patents relating to pharmaceuticals were litigated in the UK Courts. The selected cases in this review involved
Sarah-Jane Crawford +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
THE LIMITS OF RECOURSE TO FORCE IN THE CONTEXT OF CONTEMPORARY GEOPOLITICS [PDF]
Recourse to force represents a highly controversial subject matter, given its political sensitivity, as well as the legal framework that authorizes it.
Sandra Sophie-Elise OLĂNESCU
doaj
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
The Doctoral Student’s Responsibility for Violation of Ethical Standards During Doctoral Studies
Intellectual property law enjoys the most expansive and branching evolution of the last century, both in terms of national regulations and in terms of signed international conventions and adopted Community directives, as evidenced even by established ...
Maria Cristiana Ieremie
doaj
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source

