Results 41 to 50 of about 87,798 (251)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Effectiveness of wound infusion of 0.2% ropivacaine by patient control analgesia pump after minithoracotomy aortic valve replacement: a randomized, double-blind, placebo-controlled trial

BMC Anesthesiology, 2020
Background Local anesthetic wound infusion has become an invaluable technique in multimodal analgesia. The effectiveness of wound infusion of 0.2% ropivacaine delivered by patient controlled analgesia (PCA) pump has not been evaluated in minimally ...
Gordan Mijovski, Matej Podbregar, Juš Kšela, Matej Jenko, Maja Šoštarič   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Nursing research on infusion pump used in blood transfusion for infants

Huli yanjiu, 2004
Objective: to observe the effect of infusion pump used in blood transfusion for infants. Method: a total of 40 patients undergoing blood transfusion were divided into test and control groups randomly. Infants of test group were accepted blood transfusion
龚任存, 马萍焕, 吕玉江, 邢金秀, 王金聪   +4 more
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Experience on the Use of Subcutaneous Placement of Complete Embedding Infusion Pump in Intraabdominal Chemotherapy

Huli yanjiu, 1997
Subcutaneous placement of complete embedding infusion pump were used in 286 chemotherapy patients with Gastrointestinal carcinoma.There were 451 pumps.Infection developed in 32 cases in them,pump inclination occurred in 56 cases and catheter obstruction ...
李金华
doaj  

Short- and long-term complications of insulin pump therapy in children and adolescents with type 1 diabetes: a multicenter cross-sectional study from Saudi Arabia

Therapeutic Advances in Chronic Disease
Background: Insulin pump therapy improves glycemic control in children with type 1 diabetes but is associated with technical and dermatological complications that can impact adherence. Research on these adverse effects in pediatric populations is limited.
Ayman Bakkar, Enad Althobaiti, Ibtisam Alqahtani, Lujain A Abualkhair, Naglaa M Kamal, Mohammed Althobaiti, Turki Alotaibi, Lura Habib, Lujain Alharthi, Saad Aljuaid, Maha Althuwaybi, Haneen Alshehri, Muhannad Alotaibi, Wael Kamal, Mutlaq Aljuaid, Samia Almalki, Abdulaziz Alsaedi   +16 more
doaj   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Iloprost infusion by a new device as a portable syringe pump: safety, tolerability and agreement

Italian Journal of Medicine, 2012
Background Iloprost, prostacyclin (PGI2) analogue, effective in treatment of peripheral arterial disease, secondary Raynaud's phenomenon (RP) to connective tissue disease (CTD), vasculitis, pulmonary hypertension, is usually infused through peristaltic ...
Paola Faggioli, Alba Sciascera, Leopoldo Giani, Antonino Mazzone   +3 more
doaj   +1 more source