Results 91 to 100 of about 11,255 (224)

High Concordance of Copy Number Variants Detected by Chromosomal Microarray and Exome Sequencing in Clinical Diagnostics

open access: yesClinical Genetics, EarlyView.
To assess the relevance of exome sequencing as a first‐tier diagnostic tool, three aspects were investigated: detection of copy number variants (CNVs) from exomes as compared to chromosomal microarray, clinically‐relevant CNVs across all sizes, and additional diagnostic utilities (uniparental disomy and triploidy).
Rivka Birnbaum   +13 more
wiley   +1 more source

The Children's Eating and Drinking Activity Scale: Interrater reliability, concurrent validity, and responsiveness

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This paper evaluated the interrater reliability, concurrent validity and responsiveness of the Children's Eating and Drinking Activity Scale ‐ a measure of functional outcome for children with paediatric feeding disorder. Abstract Aim To assess the interrater reliability, concurrent validity, and responsiveness of the Children's Eating and Drinking ...
Ericka Joinelle Mantaring   +4 more
wiley   +1 more source

Safer Access With Fewer Transfusions: Revisiting Platelet Thresholds in Pediatric Central Venous Catheterization

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Background Central venous catheters (CVCs) are essential in pediatric hematology‐oncology, for the administration of chemotherapy and supportive therapy. Thrombocytopenia increases the risk of bleeding and current guidelines recommend prophylactic platelet transfusions below 40–50 × 109/L, though evidence is limited and transfusions entail ...
Alessandro Raffaele   +8 more
wiley   +1 more source

Plant‐produced encapsulin displays non‐typhoidal Salmonella enterica antigens and assembles into mosaic nanoparticles

open access: yesThe FEBS Journal, EarlyView.
This study investigates the potential of encapsulin as an antigen display platform for the development of a candidate Salmonella vaccine for poultry. Encapsulin constructs were transiently expressed in Nicotiana benthamiana where they accumulated to high levels.
Carly A. Charron   +6 more
wiley   +1 more source

Towards inclusive HIV cure development: Identifying important and acceptable HIV cure attributes and strategies among people with HIV in the Netherlands

open access: yesHIV Medicine, EarlyView.
Abstract Objectives Initial HIV cure interventions may not meet expert‐defined target product profiles (TPPs; desired treatment attributes). Understanding how people with HIV perceive ideal and likely HIV cure attributes is essential. This study examined which optimal TPP attributes people with HIV consider important and which minimum attributes and ...
Maaike A. J. Noorman   +6 more
wiley   +1 more source

Effects of implementing a standardized protocol for identifying and treating iron‐deficiency anemia in pregnancy

open access: yesPregnancy
Introduction Iron‐deficiency anemia is a common finding in pregnancy; however, current obstetric practice lacks standardized recommendations for its diagnosis and treatment during pregnancy, and data are limited regarding the effectiveness of diagnosis ...
Alicia M. Mccarthy   +3 more
doaj   +1 more source

Time to Hang Up the Gloves: A Scoping Review of Evidence on Non‐Sterile Glove Use During Intravenous Antimicrobial Preparation and Administration

open access: yesJournal of Advanced Nursing, EarlyView.
ABSTRACT Aims To systematically summarise evidence related to the use of non‐sterile gloves when preparing and administering intravenous antimicrobials. Design Scoping review. Methods A rigorous scoping review was undertaken following Arksey and O'Malley's (2005) framework and the modified Preferred Reporting Items for Systematic Reviews and Meta ...
Natasya Raja Azlan   +10 more
wiley   +1 more source

Acute Efficacy of Pulsed‐Field Ablation of the Mitral Isthmus Using a Pentaspline Catheter and Two Different Ablation Settings

open access: yesJournal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction There is limited data regarding the use of pulsed‐field ablation (PFA) for mitral isthmus (MI) ablation in patients with non‐paroxysmal atrial fibrillation (AF). Our aim was to assess the acute efficacy of MI ablation using a pentaspline PFA catheter with two different ablation settings.
Josef Hornof   +13 more
wiley   +1 more source

Antimicrobial Resistance and Infant Mortality in Sri Lanka: A Retrospective Cohort Study

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Objective Sepsis is a major cause of mortality among children, with the highest burden evident in neonates and young infants, particularly, in resource‐constrained healthcare settings. Despite this burden, there are insufficient published data to delineate the epidemiology of neonatal sepsis from many of these settings.
Gayana P. S. Gunaratna   +8 more
wiley   +1 more source

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