ABSTRACT Objectives Pediatric acute myeloid leukemia (AML) chemotherapy regimens are frequently burdened by fever episodes, systemic inflammation and bloodstream infections (BSI). Mucosal barrier injury may contribute to these complications, but its role in childhood AML remains uninvestigated.
Carla Warley Kjær +8 more
wiley +1 more source
ABSTRACT Background Iron overload in chronic kidney disease contributes to oxidative injury. The role of iron chelators, standard in transfusion‐related overload, remains unclear in chronic kidney disease. Aim To evaluate the efficacy and safety of iron chelators in adults with chronic kidney disease.
Humam Emad Rajha +6 more
wiley +1 more source
Malposition of a Peripherally Inserted Central Catheter Into the Internal Vertebral Venous Plexus in a Neonate With Central Nervous System Malformations. [PDF]
Oshima M +4 more
europepmc +1 more source
Rare Variants in PFIC‐Related Genes Among Adults With Intrahepatic Cholestasis
ABSTRACT Aim Biallelic pathogenic variants in progressive familial intrahepatic cholestasis (PFIC)‐related genes cause severe pediatric cholestasis. However, the clinical significance of heterozygous variants in adult intrahepatic cholestasis remains unclear.
Shunji Hirose +9 more
wiley +1 more source
Exploring Potential Drug-Drug Interactions: A Cross-Sectional Study of 1 Million e-Prescriptions Across Medical Specialties in Shiraz, Iran (2021-2024). [PDF]
Porbaha P +5 more
europepmc +1 more source
Abstract Parenteral iron is widely prescribed by medical practitioners, with more than 600 000 outpatient prescriptions dispensed in 2025 through the Australian Pharmaceutical Benefits Scheme. While intravenous iron has transformed the management of iron deficiency, hypophosphataemia is now recognised as a common complication, with incidences reported ...
Brenda Ta +3 more
wiley +1 more source
Reduction in Prostacyclin Infusion Errors Following a Comprehensive Multidisciplinary Process Transformation for Hospitalized Pediatric Patients with Pulmonary Hypertension: A Quality Improvement Project. [PDF]
Kirk C, Davis A, Yung D.
europepmc +1 more source
Large‐scale meta‐analysis of infection risk with JAK–STAT inhibitors in 29,000 patients
In this large meta‐analysis of 74 randomized controlled trials involving more than 29,000 patients, JAK–STAT inhibitors were associated with an increased risk of influenza, bronchitis and herpes infections, particularly herpes zoster, while an increased risk of serious opportunistic or fungal infections was not observed.
Máté Krebs +10 more
wiley +1 more source
Parenteral clomipramine for depression or obsessive-compulsive disorder: a systematic review and meta-analysis. [PDF]
Ioannou M +8 more
europepmc +1 more source
Artificial Intelligence in Neonatal Care: The Breadth of Promise, the Depth of Challenge—An Overview
ABSTRACT Artificial intelligence (AI) is becoming an integral tool in clinical care. The recent position statement by the Royal Australasian College of Physicians (RACP) provides a timely practical blueprint on implementing and monitoring the use of AI in clinical practice.
N. M. Lai +3 more
wiley +1 more source

