Results 111 to 120 of about 11,668 (257)

Pronounced Reductions in Plasma Citrulline Indicate Severe Intestinal Mucosal Barrier Injury During Induction Therapy for Pediatric Acute Myeloid Leukemia

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Objectives Pediatric acute myeloid leukemia (AML) chemotherapy regimens are frequently burdened by fever episodes, systemic inflammation and bloodstream infections (BSI). Mucosal barrier injury may contribute to these complications, but its role in childhood AML remains uninvestigated.
Carla Warley Kjær   +8 more
wiley   +1 more source

Safety and Efficacy of Iron Chelators in Patients With Chronic Kidney Disease: A Systematic Review and Meta‐Analysis

open access: yesHemodialysis International, EarlyView.
ABSTRACT Background Iron overload in chronic kidney disease contributes to oxidative injury. The role of iron chelators, standard in transfusion‐related overload, remains unclear in chronic kidney disease. Aim To evaluate the efficacy and safety of iron chelators in adults with chronic kidney disease.
Humam Emad Rajha   +6 more
wiley   +1 more source

Rare Variants in PFIC‐Related Genes Among Adults With Intrahepatic Cholestasis

open access: yesHepatology Research, EarlyView.
ABSTRACT Aim Biallelic pathogenic variants in progressive familial intrahepatic cholestasis (PFIC)‐related genes cause severe pediatric cholestasis. However, the clinical significance of heterozygous variants in adult intrahepatic cholestasis remains unclear.
Shunji Hirose   +9 more
wiley   +1 more source

Hypophosphataemia following iron infusion: a narrative review of an increasingly recognised complication

open access: yesInternal Medicine Journal, EarlyView.
Abstract Parenteral iron is widely prescribed by medical practitioners, with more than 600 000 outpatient prescriptions dispensed in 2025 through the Australian Pharmaceutical Benefits Scheme. While intravenous iron has transformed the management of iron deficiency, hypophosphataemia is now recognised as a common complication, with incidences reported ...
Brenda Ta   +3 more
wiley   +1 more source

Large‐scale meta‐analysis of infection risk with JAK–STAT inhibitors in 29,000 patients

open access: yesJournal of the European Academy of Dermatology and Venereology, EarlyView.
In this large meta‐analysis of 74 randomized controlled trials involving more than 29,000 patients, JAK–STAT inhibitors were associated with an increased risk of influenza, bronchitis and herpes infections, particularly herpes zoster, while an increased risk of serious opportunistic or fungal infections was not observed.
Máté Krebs   +10 more
wiley   +1 more source

Parenteral clomipramine for depression or obsessive-compulsive disorder: a systematic review and meta-analysis. [PDF]

open access: yesActa Neuropsychiatr
Ioannou M   +8 more
europepmc   +1 more source

Artificial Intelligence in Neonatal Care: The Breadth of Promise, the Depth of Challenge—An Overview

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Artificial intelligence (AI) is becoming an integral tool in clinical care. The recent position statement by the Royal Australasian College of Physicians (RACP) provides a timely practical blueprint on implementing and monitoring the use of AI in clinical practice.
N. M. Lai   +3 more
wiley   +1 more source

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