Results 91 to 100 of about 11,668 (257)

CEFEPIME/ENMETAZOBACTAM: Physicochemical Stability of a Novel β-Lactam/β-Lactamase Inhibitor Combination in Syringes and Elastomeric Devices

open access: yesAntibiotics
Background: Cefepime/enmetazobactam (FEP/META) is a novel fixed-dose β-lactam/β-lactamase inhibitor combination. The objective was to study the physicochemical stability of the approved daily dose in polypropylene syringes and elastomeric devices over a ...
Akim Chayem   +9 more
doaj   +1 more source

Prognostic models for predicting sight‐threatening retinopathy of prematurity in preterm infants: A systematic review

open access: yesActa Ophthalmologica, EarlyView.
Abstract To identify, describe and critically appraise studies developing and/or validating models for predicting sight‐threatening retinopathy of prematurity (ROP) in preterm infants undergoing screening in neonatal intensive care units. PubMed, Embase via Ovid, trial registers, and grey literature were searched from inception to 21 October 2025 ...
Stella Moutzouri   +7 more
wiley   +1 more source

THESS‐ROP study: Development of a prediction model for treatment‐warranted retinopathy of prematurity and external validation of postnatal weight‐gain‐based models in Greece

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To develop THESS‐ROP, a novel prediction model for treatment‐warranted retinopathy of prematurity (TW‐ROP) and compare its performance with four established models in a Greek cohort of consecutively screened preterm infants. Methods This ambispective cohort study included all 526 infants screened for ROP (2016–2022) at the 2nd ...
Stella Moutzouri   +6 more
wiley   +1 more source

Influencia de la formulación de la glutamina en sus efectos sobre los sistemas antioxidantes y de destoxificación hepática en la rata Effects of glutamine on antioxidants systems and hepatic detoxification in rats: influence of formulation

open access: yesNutrición Hospitalaria, 2004
Objetivos: El objeto de este estudio es valorar el efecto que la suplementación de dietas parenterales con L-glutamina o con L-alanil-L-glutamina ejerce sobre el equilibrio oxidante/antioxidante hepático y sobre los sistemas de destoxificación mediados ...
J. J. Ortiz de Urbina   +5 more
doaj  

Critically Ill Children Show Disrupted Sleep Patterns and Atypical Electroencephalograms: An Observational Cohort Study

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim Sleep disruptions are common in hospitalised children. This study described sleep in critically ill and non‐critically ill hospitalised children, including young infants and patients with central nervous system injuries. Methods This observational cohort study included two groups: critically ill children admitted to a paediatric intensive ...
Eris van Twist   +9 more
wiley   +1 more source

Meta‐Analysis: Chronic Gastrointestinal Symptoms and Comorbidities in Hypermobile Ehlers–Danlos Syndrome and Hypermobility Spectrum Disorders

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
This meta‐analysis reveals that a significant proportion of patients with hEDS/HSD experience gastrointestinal symptoms. The most prevalent symptoms include heartburn, abdominal pain, constipation, and nausea. There is a notable overlap of hEDS/HSD with chronic fatigue, DGBI, GERD, migraine, and orthostatic intolerance.
Dmitrii Kulin   +9 more
wiley   +1 more source

Acute chest pain following parenteral infusion

open access: yesDeutsches Ärzteblatt international, 2021
Manuel, Rattka   +2 more
openaire   +2 more sources

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy