Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
wiley +1 more source
"Double trouble": the impact of iron infusion and antiresorptive therapy on calcium-phosphate homeostasis. [PDF]
Stokes G, Sheu A, Girgis CM, White CP.
europepmc +1 more source
ABSTRACT Childhood stunting remains a public health challenge in Thailand. While national surveys provide prevalence estimates, there is limited understanding of the multilevel influences shaping child feeding practices. This qualitative study aimed to explore individual, familial, and socioenvironmental determinants of child feeding practices among ...
Thanit Vinitchagoon +8 more
wiley +1 more source
ABSTRACT Background Nutrition during hospitalisation following critical illness is fundamental to rehabilitation, but provision is often poor. Aim To analyse the process of delivering nutrition to post‐ICU patients on the ward. Study Design This work forms part of a mixed methods study.
Sarah Vollam +5 more
wiley +1 more source
Treatment-Resistant Hypophosphataemia After Ferric Carboxymaltose: Expanding the Spectrum of 6h Syndrome (Hypophosphataemia, Hyperphosphaturia, Hypovitaminosis D, Hypocalcaemia, Secondary Hyperparathyroidism, High Fibroblast Growth Factor-23). [PDF]
Rashid L.
europepmc +1 more source
High‐Concentration Antibody Formulation via Solvent‐Based Dehydration
Amorphous solid antibodies are encapsulated into hydrogel microparticles through a solvent‐based dehydration process. The solvent extracts water from antibody solution droplets, causing the antibody to concentrate, and precipitation of the antibody into amorphous solid is induced.
Talia Zheng +3 more
wiley +1 more source
Cyclic infusion mitigates liver dysfunction associated with continuous total parenteral nutrition in a novel murine model. [PDF]
Willis NB +6 more
europepmc +1 more source
Dysregulated cholesterol metabolism, driven by a complex array of mechanisms, is a defining characteristic of glioblastoma (GBM). In this study, supramolecular nanoscavengers are engineered by harnessing the intrinsic binding affinity between endogenous small‐molecule cholesterol and β‐cyclodextrin (β‐CD).
Zonghua Tian +7 more
wiley +1 more source
Association of catheter-related blood stream infections and aseptic technique(s) used in administration of parenteral nutrition: a systematic review and narrative synthesis. [PDF]
Fletcher J, Malhi H, Topping A.
europepmc +1 more source
Implantable Drug Delivery Systems for Skeletal Muscles and Eyes
This review highlights the different types of recent implantable drug delivery systems (IDDS) fabricated for a use with skeletal muscles, and with eyes. It presents the developments already made and the current research directions, showing the evolution of IDDS and their great diversity.
Serge Ostrovidov +8 more
wiley +1 more source

