Results 141 to 150 of about 22,495 (292)

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source

High Concordance of Copy Number Variants Detected by Chromosomal Microarray and Exome Sequencing in Clinical Diagnostics

Clinical Genetics, EarlyView.
To assess the relevance of exome sequencing as a first‐tier diagnostic tool, three aspects were investigated: detection of copy number variants (CNVs) from exomes as compared to chromosomal microarray, clinically‐relevant CNVs across all sizes, and additional diagnostic utilities (uniparental disomy and triploidy).
Rivka Birnbaum, Maya Slovik, Shamir Zenvirt, Ilana Livyatan, Israel Altman, Shiri Gershon, Jonathan Rips, Hagit Daum, Chaggai Rosenbluh, Orly Elpeleg, Vardiella Meiner, Ayala Frumkin, Hagar Mor‐Shaked, Tamar Harel   +13 more
wiley   +1 more source

The Children's Eating and Drinking Activity Scale: Interrater reliability, concurrent validity, and responsiveness

Developmental Medicine &Child Neurology, EarlyView.
This paper evaluated the interrater reliability, concurrent validity and responsiveness of the Children's Eating and Drinking Activity Scale ‐ a measure of functional outcome for children with paediatric feeding disorder. Abstract Aim To assess the interrater reliability, concurrent validity, and responsiveness of the Children's Eating and Drinking ...
Ericka Joinelle Mantaring, Sheung Yu Sylfiana Wong, Michelle McInerney, Vicky Thorpe, Alexandra Stewart   +4 more
wiley   +1 more source

Safer Access With Fewer Transfusions: Revisiting Platelet Thresholds in Pediatric Central Venous Catheterization

European Journal of Haematology, EarlyView.
ABSTRACT Background Central venous catheters (CVCs) are essential in pediatric hematology‐oncology, for the administration of chemotherapy and supportive therapy. Thrombocytopenia increases the risk of bleeding and current guidelines recommend prophylactic platelet transfusions below 40–50 × 109/L, though evidence is limited and transfusions entail ...
Alessandro Raffaele, Carlo Maria Ferlini, Marta Gazzaneo, Piero Giovanni Romano, Bilge Rol, Francesco Delle Cave, Stella Boghen, Tommaso Mina, Marco Zecca   +8 more
wiley   +1 more source

Complications and Monitoring – Guidelines on Parenteral Nutrition, Chapter 11

GMS German Medical Science, 2009
Compared to enteral or hypocaloric oral nutrition, the use of PN (parenteral nutrition) is not associated with increased mortality, overall frequency of complications, or longer length of hospital stay (LOS). The risk of PN complications (e.g.
Working group for developing the guidelines for parenteral nutrition of The German Association for Nutritional Medicine, Rittler, P., Parhofer, K., Jauch, K. W., Hartl, W. H.   +4 more
doaj  

Plant‐produced encapsulin displays non‐typhoidal Salmonella enterica antigens and assembles into mosaic nanoparticles

The FEBS Journal, EarlyView.
This study investigates the potential of encapsulin as an antigen display platform for the development of a candidate Salmonella vaccine for poultry. Encapsulin constructs were transiently expressed in Nicotiana benthamiana where they accumulated to high levels.
Carly A. Charron, Angelo Kaldis, Shabnam Shamriz, Justin B. Renaud, Moussa S. Diarra, Christopher P. Garnham, Rima Menassa   +6 more
wiley   +1 more source

Towards inclusive HIV cure development: Identifying important and acceptable HIV cure attributes and strategies among people with HIV in the Netherlands

HIV Medicine, EarlyView.
Abstract Objectives Initial HIV cure interventions may not meet expert‐defined target product profiles (TPPs; desired treatment attributes). Understanding how people with HIV perceive ideal and likely HIV cure attributes is essential. This study examined which optimal TPP attributes people with HIV consider important and which minimum attributes and ...
Maaike A. J. Noorman, John B. F. de Wit, Tamika A. Marcos, Sarah E. Stutterheim, Thijs Albers, Kai J. Jonas, Chantal Den Daas   +6 more
wiley   +1 more source

Time to Hang Up the Gloves: A Scoping Review of Evidence on Non‐Sterile Glove Use During Intravenous Antimicrobial Preparation and Administration

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aims To systematically summarise evidence related to the use of non‐sterile gloves when preparing and administering intravenous antimicrobials. Design Scoping review. Methods A rigorous scoping review was undertaken following Arksey and O'Malley's (2005) framework and the modified Preferred Reporting Items for Systematic Reviews and Meta ...
Natasya Raja Azlan, Debbie Massey, Lesley Andrew, Amanda Towell‐Barnard, Seng Giap Marcus Ang, Carol Crevacore, Martina Costello, Aaron Alejandro, Weiting Liu, Naila Zaman, Peta‐Anne Zimmerman   +10 more
wiley   +1 more source

Tratamiento dietético-nutricional en la enteritis rádica crónica: A propósito de un caso clínico complejo Dietetic-nutritional treatment in chronic radiation enteritis: Apropos of a complex clinical case

Nutrición Hospitalaria, 2003
Presentamos un caso clínico de enteritis rádica crónica seguido durante 34 meses, cuyas características destacables son las siguientes: Paciente de 60 años con adenocarcinoma de recto que requirió hemicolectomia izquierda (Hartmann), recibiendo ...
A. Fernández de Bustos, A. M.ª Pita Mercé   +1 more
doaj  

Acute Efficacy of Pulsed‐Field Ablation of the Mitral Isthmus Using a Pentaspline Catheter and Two Different Ablation Settings

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Introduction There is limited data regarding the use of pulsed‐field ablation (PFA) for mitral isthmus (MI) ablation in patients with non‐paroxysmal atrial fibrillation (AF). Our aim was to assess the acute efficacy of MI ablation using a pentaspline PFA catheter with two different ablation settings.
Josef Hornof, Marek Hozman, Dalibor Heřman, Oleksii Romanenko, Sabri Hassouna, Jana Veselá, Věra Filipcová, Lukáš Povišer, Jakub Karch, Jana Hozmanová, Lucie Znojilová, Anna Molová, Vojtěch Pěnkava, Pavel Osmančík   +13 more
wiley   +1 more source