Results 141 to 150 of about 539,277 (324)

Endotypes in Immune Mediated Drug Reactions: Present and Future of Relevant Biomarkers. An EAACI Task Force Report

open access: yesAllergy, EarlyView.
ABSTRACT Drug‐induced immune reactions are an important burden for patients and health systems. They can be classified into immediate‐drug hypersensitivity reactions (IDHRs) and delayed‐DHRs (DDHRs) based on their phenotype. Drugs do not always behave as allergens and need to bind to proteins, forming adducts.
C. Mayorga   +7 more
wiley   +1 more source

Influencia de la formulación de la glutamina en sus efectos sobre los sistemas antioxidantes y de destoxificación hepática en la rata Effects of glutamine on antioxidants systems and hepatic detoxification in rats: influence of formulation

open access: yesNutrición Hospitalaria, 2004
Objetivos: El objeto de este estudio es valorar el efecto que la suplementación de dietas parenterales con L-glutamina o con L-alanil-L-glutamina ejerce sobre el equilibrio oxidante/antioxidante hepático y sobre los sistemas de destoxificación mediados ...
J. J. Ortiz de Urbina   +5 more
doaj  

Simultaneous Ex Situ Normothermic Perfusion of Paired Kidneys in Pigs

open access: yesArtificial Organs, EarlyView.
This pig model of simultaneous perfusion of paired kidneys in normothermia suggests that intra‐individual variation is relatively low, enabling one kidney to be employed as a reliable comparator of the other kidney for assessing treatments before kidney transplantation.
Margaux Navez   +12 more
wiley   +1 more source

A narrative literature review about alpha‐lipoic acid role in dry eye and ocular surface disease

open access: yesActa Ophthalmologica, EarlyView.
Abstract Ocular surface diseases (OSD) include various conditions that affect the eye's surface, causing discomfort and pain. One such condition, dry eye disease (DED), is a multifactorial disorder that significantly impacts patients' quality of life, with prevalence rates ranging from 5% to 50% and higher incidence in women.
Antonio J. Mateo Orobia   +4 more
wiley   +1 more source

Postoperative delirium after major orthopedic surgery. [PDF]

open access: yes, 2020
BACKGROUND: Postoperative delirium (POD) is one of the most common complications in older adult patients undergoing elective surgery. Few studies have compared, within the same institution, the type of surgery, risk factors and type of anesthesia and ...
Magid, Steven K.   +3 more
core   +1 more source

Challenges and Considerations in Manipulating Oral Dosage Forms in Paediatric Healthcare Settings: A Narrative Review

open access: yesActa Paediatrica, EarlyView.
A substantial proportion of oral drug administrations in children require manipulation due to the lack of age‐appropriate formulations. Common methods such as splitting, crushing, and dispersing tablets in fluids can compromise dose accuracy because of e.g., drug solubility.
M. Paulsson   +5 more
wiley   +1 more source

Lymphocytes cross-matching as retrospective tool for hyper-acute rejection diagnosis in heart transplantation.

open access: yesTransplantation Reports, 2020
Background: Lymphocyte cross-matching (CDC) is considered as important screening test that is unfrequently performed preoperatively in heart transplantation procedures.
Tomasz Urbanowicz   +3 more
doaj  

Acute onset neurological deficits and hypocalcaemia associated with nutritional secondary hyperparathyroidism in three juvenile servals (Leptailurus serval)

open access: yesAustralian Veterinary Journal, EarlyView.
Nutritional secondary hyperparathyroidism is a metabolic disorder caused by an imbalance in calcium homeostasis and is typically associated with the feeding of a calcium‐deficient diet. Nutritional secondary hyperparathyroidism has been reported in domestic species, including cats and dogs, as well as captive carnivores and wildlife including lions ...
JL Austen   +5 more
wiley   +1 more source

Efficacy and safety of oral decitabine/cedazuridine in the chronic myelomonocytic leukaemia subpopulations from phase 2 and 3 studies

open access: yesBritish Journal of Haematology, EarlyView.
A retrospective analysis of patients with chronic myelomonocytic leukaemia treated with oral decitabine 35 mg + cedazuridine 100 mg suggested favourable outcomes, particularly in higher risk patients. The results provide a rationale for further prospective study of oral decitabine/cedazuridine to identify subgroups of this population who would benefit ...
Michael R. Savona   +16 more
wiley   +1 more source

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