Results 141 to 150 of about 12,039 (307)

Shoulder‐Tip Pain After Laparoscopic Surgery: A Narrative Review of Intraperitoneal Anaesthesia

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Background and Aims Shoulder‐tip pain is a common and distressing side effect following laparoscopic surgery. Standard systemic analgesic regimens are used to manage postoperative pain but are often associated with side effects such as nausea and vomiting.
Jason Arsanious   +2 more
wiley   +1 more source

Bone disease in young patients on long-term parenteral nutrition: The role of pamidronate

open access: yes, 2002
The purpose of our study was to investigate the possible therapeutic effects of endovenous infusions of pamidronate in young patients on total parenteral nutrition (TPN) from birth.
Ventura A.   +4 more
core  

Marked variation in eligibility criteria across registrational trials for relapsed diffuse large B‐cell lymphoma limits applicability to clinical practice

open access: yesBritish Journal of Haematology, EarlyView.
Summary Therapeutic options for relapsed or refractory diffuse large B‐cell lymphoma (rDLBCL) have expanded following accelerated approvals based largely on surrogate end‐points, yet confirmatory studies have not consistently reproduced these benefits across all agents, and outcomes for many patients remain poor.
Elizabeth Goodall   +11 more
wiley   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

Acute chest pain following parenteral infusion

open access: yesDeutsches Ärzteblatt international, 2021
Manuel, Rattka   +2 more
openaire   +2 more sources

Concurrent Denosumab and Parenteral Iron Therapy Precipitating Severe Hypocalcemia and Hypophosphatemia.

open access: yes
Denosumab-induced hypocalcemia and iron infusion-related hypophosphatemia are both well described. We describe a case of severe hypocalcemia and hypophosphatemia following sequential denosumab and parenteral iron administration.
Luo, J, Ye, S, Nguyen, HH, Grill, V
core   +1 more source

Cancer pain: current practice and emerging targets

open access: yesBritish Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye   +5 more
wiley   +1 more source

Impact of Oral Sebetralstat on Anxiety Associated With Hereditary Angioedema Attacks

open access: yesClinical &Experimental Allergy, EarlyView.
In the phase 3 KONFIDENT trial of oral sebetralstat for on‐demand treatment of hereditary angioedema attacks, many attacks induced moderate‐to‐extreme anxiety. Sebetralstat reduced anxiety versus placebo; time to reductions agreed with trial endpoints, such as time to beginning of symptom relief.
Timothy Craig   +24 more
wiley   +1 more source

Rebound Pruritus and Urticaria After Discontinuation of Chronic Antihistamine Use—A Scoping Review

open access: yesClinical &Experimental Allergy, EarlyView.
Rebound pruritus and urticaria have been reported after discontinuation of chronic cetirizine or levocetirizine use only. Symptoms typically occur within 0.5–5 days after stopping therapy and appear more frequently reported in female patients. Re‐initiation of antihistamines is the most commonly effective management strategy, highlighting the need for ...
Jun Jie Benjamin Seng   +2 more
wiley   +1 more source

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