Results 171 to 180 of about 20,436 (308)

Comparative Pharmacokinetics of Intranasal or Intramuscular Atipamezole in Unsedated Dogs and Efficacy for Reversal of Xylazine Sedation

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT The objectives of this study were to evaluate ATIP pharmacokinetics (PK) in healthy Beagle dogs after IM and IN dosing (Phase I), and to compare the rate of reversal of IM versus IN routes for xylazine (XYL) sedation (Phase II). This study was comprised of two sequential, randomized, crossover experiments. The initial PK study dosed ATIP by IN
Vanessa E. Cowan   +7 more
wiley   +1 more source

Risk of Treatment Failure in Outpatient Parenteral Antimicrobial Therapy From an Academic Medical Center in Kentucky. [PDF]

open access: yesOpen Forum Infect Dis
Worsham Behal K   +5 more
europepmc   +1 more source

Pharmacokinetics of Long‐Acting Ampicillin and Its Impact on the Gut Microbiome and Resistome in Rhesus Macaques (Macaca mulatta)

open access: yesJournal of Veterinary Pharmacology and Therapeutics, EarlyView.
ABSTRACT Injectable antimicrobials with documented prolonged dosing intervals (> 48 h) for use in rhesus macaques are sparse. The objective of our study was to assess the pharmacokinetics, urine excretion, and effects on gut microbiome and resistome of intramuscular administered long‐acting formulation of ampicillin (Albipen LA) in macaques.
Annemiek Maaskant   +9 more
wiley   +1 more source

Diagnosis and Management of Stevens‐Johnson Syndrome and Toxic Epidermal Necrolysis in Pediatric Patients: A Systematic Review of Clinical Guidelines and Consensus Statements

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, life‐threatening mucocutaneous reactions. Pediatric mortality is lower than in adults, but children face higher risks of recurrence and long‐term sequelae. Despite disease severity, pediatric‐specific guidelines remain scarce and often extrapolated from adult ...
Rachel Creighton   +3 more
wiley   +1 more source

Enhancing Community‐Based Nursing Decision Support: Machine Learning Models for Diabetes Risk Prediction Using Home Health Nursing Notes

open access: yesPublic Health Nursing, EarlyView.
ABSTRACT Objectives This study aimed to identify high‐risk factors for type 2 diabetes and develop a machine learning (ML)–based diabetes prediction model using nursing notes from home health care. Design Retrospective cohort study. Sample A total 7896 medical records from 1747 patients aged ≥ 20 years who received home health care at a university ...
Doyeon LIM   +3 more
wiley   +1 more source

Fat overload syndrome in pediatric patients: One case and ten at risk. [PDF]

open access: yesAsia Pac J Clin Nutr
Saengpanit P   +3 more
europepmc   +1 more source

Transfusion‐related alpha‐gal syndrome: Two new cases expanding the demographic and geographic spectrum, and evidence of a diagnostic gap in allergic transfusion reaction evaluation

open access: yesTransfusion, EarlyView.
Abstract Background Transfusion‐related alpha‐gal syndrome (TRAGS) has recently been proposed as a cause of allergic transfusion reactions (ATRs) in which alpha‐gal‐specific IgE in sensitized group O (or potentially group A) recipients reacts with epitopes on group B or AB plasma‐containing components.
Mackenzie Foster   +9 more
wiley   +1 more source

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