Results 51 to 60 of about 20,436 (308)

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

British Journal of Clinical Pharmacology, EarlyView.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup, Michel Tod, Laurent Bourguignon   +2 more
wiley   +1 more source

Pharmaceutical hemostasis at peptic ulcer bleeding: state-of-the-art and perspectives

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2013
Aim of investigation. To study efficacy of parenteral proton pump inhibitors in patients with ulcerative gastroduodenal bleeding.Material and methods. Overall 71 patients were included in original study.
A. A. Schegolev, O. A. Al Sabunchi, S. A. Valetov, A. V. Pavlychev, Ye. A. Klochneva   +4 more
doaj  

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

INDICACIÓN ADECUADA DE LÍQUIDOS Y ELECTROLITOS PARENTERALES EN ADULTOS HOSPITALIZADOS: VALORACIÓN DE UNA ESTRATEGIA DE APRENDIZAJE Y SUPERVISIÓN

Revistas Argentina de Medicina, 2019
Introducción. Muchos pacientes hospitalizados requieren fluidos endovenosos para prevenir o corregir problemas relacionados con su estado actual de líquidos y trastornos electrolíticos.
Frederike Urban, Lucía Lossetti, Miguel Ángel Castiarena, Oscar Furlong, Daniela Piedrabuena Toffoletti, Mercedes Galíndez, Melisa Spessot Celi, María Sol Bruno, Fernando Tortosa   +8 more
doaj   +2 more sources

Incidence of local complications and risk factors associated with peripheral intravenous catheter in neonates

Revista da Escola de Enfermagem da USP, 2016
OBJECTIVE To evaluate the incidence of complications related to the use of peripheral intravenous catheter in neonates and identify the associated risk factors. METHOD Prospective cohort study conducted in a Neonatal Intensive Care Unit.
Mitzy Tannia Reichembach Danski, Priscila Mingorance, Derdried Athanasio Johann, Stela Adami Vayego, Jolline Lind   +4 more
doaj   +1 more source

Cutaneous phototoxic reaction to intravenous micafungin in the outpatient setting: A case report

Clinical Infection in Practice, 2021
Background: Signal Transducer and Activator of Transcription 1 (STAT1) Gain of Function (GoF) mutations can predispose to chronic mucocutaneous candidiasis (CMC).
Arthur Price, Thomas C. Morris, Helena A. White, Ryan A. Hamilton   +3 more
doaj   +1 more source

Outpatient treatment of decompensated heart failure: A systematic review and study level meta‐analysis

ESC Heart Failure, Volume 12, Issue 2, Page 761-769, April 2025.
Abstract Patients with acutely decompensated heart failure (ADHF) are usually admitted to hospital for management. There is growing interest in delivering intravenous (IV) diuretic therapy at home, in the community or at hospital day‐care units; the safety and effectiveness of outpatient‐based management (OPM) for ADHF has not been established.
Jameela Bahar, Amna Rahman, Grace W.Y. Wong, Rajiv Sankaranarayanan, Fozia Z. Ahmed, Rebecca Taylor, Ahmet Fuat, Iain Squire, John G.F. Cleland, Gregory Y.H. Lip, James H.P. Gamble, Sundas Masudi, Prince Josiah S. Joseph, Kenneth Y.K. Wong   +13 more
wiley   +1 more source

Medical injection and infusion practices among HIV-seronegative people and people living with HIV: a behavioural survey of 10 HIV testing and opportunistic infections/antiretroviral therapy sites in Cambodia

BMJ Open, 2022
Objectives In late 2014, an HIV outbreak occurred in rural Cambodia among villagers who received medical injections from unlicensed medical providers, justifying the need to assess medical injection practices among those who are at risk of acquiring and ...
Vonthanak Saphonn, Keovathanak Khim, Kennarey Seang, Kartavya Vyas, Dyna Khuon, Pamina Gorbach   +5 more
doaj   +1 more source

Pre-operative optimisation employing dopexamine or adrenaline for patients undergoing major elective surgery: a cost-effectiveness analysis [PDF]

, 2002
<b>Objective</b>: To compare the cost and cost-effectiveness of a policy of pre-operative optimisation of oxygen delivery (using either adrenaline or dopexamine) to reduce the risk associated with major elective surgery, in high-risk patients.
Claxton, K., Fenwick, E., Sculpher, M.J., Wilson, J.   +3 more
core   +1 more source

Intravenous versus subcutaneous drug administration. Which do patients prefer? A systematic review [PDF]

, 2014
BACKGROUND: Intravenous (IV) drug delivery is commonly used for its rapid administration and immediate drug effect. Most studies compare IV to subcutaneous (SC) delivery in terms of safety and efficacy, but little is known about what patients prefer.
Fallowfield, Lesley J, Harder, Helena, Jenkins, Valerie A, Stoner, Kelly L   +3 more
core   +1 more source