Results 51 to 60 of about 12,039 (307)

Quantitative prediction of intravenous drug interactions caused by cytochromes P450 inhibitors and inducers

British Journal of Clinical Pharmacology, EarlyView.
Background Aims Pharmacokinetic interaction studies typically focus on oral administration, but intravenous (IV) administration bypasses intestinal degradation and hepatic first‐pass metabolism, leading to distinct drug–drug interaction (DDI) magnitude. This study aimed to develop a predictive model for DDIs involving IV‐administered drugs.
Vianney Tuloup, Michel Tod, Laurent Bourguignon   +2 more
wiley   +1 more source

Contraindicated drug–drug interactions and associated adverse drug reactions in an observational cohort study of 4543 paediatric hospitalized patients

British Journal of Clinical Pharmacology, EarlyView.
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval, Sylvain Goutelle, Inesse Boussaha, Xavier Dode, Yanis Mimouni, Kim An Nguyen, Behrouz Kassai   +6 more
wiley   +1 more source

Bombas de infusão: operação, funcionalidade e segurança [PDF]

, 2002
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico.
Alves, Márcio Alexandre de Castro
core  

Outpatient treatment of decompensated heart failure: A systematic review and study level meta‐analysis

ESC Heart Failure, Volume 12, Issue 2, Page 761-769, April 2025.
Abstract Patients with acutely decompensated heart failure (ADHF) are usually admitted to hospital for management. There is growing interest in delivering intravenous (IV) diuretic therapy at home, in the community or at hospital day‐care units; the safety and effectiveness of outpatient‐based management (OPM) for ADHF has not been established.
Jameela Bahar, Amna Rahman, Grace W.Y. Wong, Rajiv Sankaranarayanan, Fozia Z. Ahmed, Rebecca Taylor, Ahmet Fuat, Iain Squire, John G.F. Cleland, Gregory Y.H. Lip, James H.P. Gamble, Sundas Masudi, Prince Josiah S. Joseph, Kenneth Y.K. Wong   +13 more
wiley   +1 more source

Pharmaceutical hemostasis at peptic ulcer bleeding: state-of-the-art and perspectives

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2013
Aim of investigation. To study efficacy of parenteral proton pump inhibitors in patients with ulcerative gastroduodenal bleeding.Material and methods. Overall 71 patients were included in original study.
A. A. Schegolev, O. A. Al Sabunchi, S. A. Valetov, A. V. Pavlychev, Ye. A. Klochneva   +4 more
doaj  

Efficacy and safety of continuous infusions with elastomeric pumps for outpatient parenteral antimicrobial therapy (OPAT): an observational study

, 2018
This study aimed to evaluate the efficacy and safety of continuous antimicrobial infusion using elastomeric pumps in an outpatient setting, while simultaneously documenting circulating antibiotic concentration exposure achieved with this mode of ...
André, P., Céline Gardiol, Thierry Buclin, Arensdorff, L., Boillat-Blanco, N., Lyne Arensdorff, Cochet, C., Pascal André, Camille Cochet, Rachel Voumard, Buclin, T., Gardiol, C., Laurent Decosterd, Decosterd, L., Noémie Boillat-Blanco, Serge de Vallière, Voumard, R., de Vallière, S.   +17 more
core   +1 more source

Lipid‐based Nano‐delivery systems as a promising strategy for the treatment of epilepsy: Current status and challenges

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy is a prevalent chronic neurological disorder characterized by abnormal neuronal electrical activity. The primary treatment modality for individuals with epilepsy (PWE) is antiseizure medication (ASM). The multiple potential factors contributing to treatment resistance in epilepsy may be attributed to the inability of ASMs to
Priya Kannan Varshini, Arunachalam Divya, Kumar Sowndharya, Parthiban Jeevitha, Selvam Manoj, Ashiq Rahman, Athil Ahamed, Ravichandiran Abirahul, Paranthaman Subash, Sulekha Khute   +9 more
wiley   +1 more source

INDICACIÓN ADECUADA DE LÍQUIDOS Y ELECTROLITOS PARENTERALES EN ADULTOS HOSPITALIZADOS: VALORACIÓN DE UNA ESTRATEGIA DE APRENDIZAJE Y SUPERVISIÓN

Revistas Argentina de Medicina, 2019
Introducción. Muchos pacientes hospitalizados requieren fluidos endovenosos para prevenir o corregir problemas relacionados con su estado actual de líquidos y trastornos electrolíticos.
Frederike Urban, Lucía Lossetti, Miguel Ángel Castiarena, Oscar Furlong, Daniela Piedrabuena Toffoletti, Mercedes Galíndez, Melisa Spessot Celi, María Sol Bruno, Fernando Tortosa   +8 more
doaj   +2 more sources

Incidence of local complications and risk factors associated with peripheral intravenous catheter in neonates

Revista da Escola de Enfermagem da USP, 2016
OBJECTIVE To evaluate the incidence of complications related to the use of peripheral intravenous catheter in neonates and identify the associated risk factors. METHOD Prospective cohort study conducted in a Neonatal Intensive Care Unit.
Mitzy Tannia Reichembach Danski, Priscila Mingorance, Derdried Athanasio Johann, Stela Adami Vayego, Jolline Lind   +4 more
doaj   +1 more source

Cutaneous phototoxic reaction to intravenous micafungin in the outpatient setting: A case report

Clinical Infection in Practice, 2021
Background: Signal Transducer and Activator of Transcription 1 (STAT1) Gain of Function (GoF) mutations can predispose to chronic mucocutaneous candidiasis (CMC).
Arthur Price, Thomas C. Morris, Helena A. White, Ryan A. Hamilton   +3 more
doaj   +1 more source