Results 271 to 280 of about 636,834 (344)

Investigating pulmonary inflammation and injury after progressive systemic inflammation in preterm fetal sheep. [PDF]

Front Physiol
Vandenberg EG, Kelly SB, Zahra VA, Lu H, Thiel A, Hooper SB, Galinsky R, Polglase GR.   +7 more
europepmc   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Approaches to stable isotope tracing and in vivo metabolomics in the cancer clinic. [PDF]

EMBO J
Faubert B, Tasdogan A.
europepmc   +1 more source

Construction of hyperthermostable d‐allulose 3‐epimerase from Arthrobacter globiformis M30 using the sequence information from Arthrobacter psychrolactophilus

FEBS Open Bio, EarlyView.
d‐Allulose can be produced from d‐fructose by d‐allulose 3‐epimerase. Based on sequence homology information, we successfully engineered thermostable mutants with the protein engineering method. By integrating positive mutations, we constructed an enzyme that exhibits hyperthermostability without a loss in the activity.
Kensaku Shimada, Kouhei Ohtani, Pushpa Kiran Gullapalli, Kazuhiko Ishikawa   +3 more
wiley   +1 more source

Bioaccessibility and Biological Activities of Phytochemicals from Wild Plant Infusions and Decoctions Before and After Simulated In Vitro Digestion. [PDF]

Plant Foods Hum Nutr
Monari S, Ferri M, Zappi A, Escórcio R, Correia VG, Cairrão A, Bento A, Pereira CS, Tassoni A.   +8 more
europepmc   +1 more source

Current trends in single‐cell RNA sequencing applications in diabetes mellitus

FEBS Open Bio, EarlyView.
Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian, Khodakaram Jahanbin, Shekoofeh Nikooei, Marzieh Rostaminejad, Arezoo Rahimi, Pedram Abdizadeh, Behnam Alipoor   +6 more
wiley   +1 more source

Dissociation of intake and incentive sensitization during intermittent- and continuous-access heroin self-administration in rats. [PDF]

Psychopharmacology (Berl)
Rakowski EA, King CP, Thompson BM, Santos G, Holmes E, Solberg Woods LC, Polesskaya O, Palmer AA, Meyer PJ.   +8 more
europepmc   +1 more source

Genetic diversity and population structure of the Taigan dog breed

FEBS Open Bio, EarlyView.
The Taigan is a rare sighthound from the mountains of Kyrgyzstan. We used DNA markers to study its genetic diversity and compare it with other sighthound breeds. Our findings show that the Taigan shares close genetic ties with the Kazakh Tazy, suggesting a common ancestry shaped by nomadic traditions and regional adaptation.
Kira Bespalova, Anastassiya Perfilyeva, Мamura Begmanova, Assel Zhaxylykova, Arailym Yerzhan, Kanagat Yergali, Almazbek Akunov, Marat Munarbek uulu, Anna Khamchukova, Almira Amirgaliyeva, Yelena Kuzovleva   +10 more
wiley   +1 more source

Mesenchymal intravenous stromal cell infusions in children with recessive dystrophic epidermolysis bullosa: MissionEB protocol for a randomised, double-blinded, placebo-controlled, two-centre, crossover trial with an internal phase I dose de-escalation phase and open-label extension. [PDF]

BMJ Open
Bageta ML, López-Balboa P, Dimairo M, Glover R, Hutchence K, Papaioannou D, Cooper C, Biggs K, Tappenden P, Ennis K, Ogboli M, Lovgren ML, Poudel P, Nadeem M, McGrath JA, Julious SA, Petrof G, Martinez AE.   +17 more
europepmc   +1 more source